Evidence map›Paper›PMID 32013251›Full record

ArticleInternational journal of molecular sciences2020

Poly(ADP-Ribose) Polymerase-3 Regulates Regeneration in Planarians.

Paul G Barghouth, Peter Karabinis, Andie Venegas, Néstor J Oviedo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Analysis of DNA Double-Stranded Breaks Using the Comet Assay in Planarians.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paul G BarghouthDepartment of Molecular and Cell Biology, University of California, Merced, CA 95340, USA.
Peter KarabinisDepartment of Molecular and Cell Biology, University of California, Merced, CA 95340, USA.
Andie VenegasDepartment of Molecular and Cell Biology, University of California, Merced, CA 95340, USA.
Néstor J OviedoDepartment of Molecular and Cell Biology, University of California, Merced, CA 95340, USA.
University of California, Merced · US

Funding

The Effects of Direct Current Stimulation in Adult TissuesR01GM132753 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI OVIEDO, NESTOR J · 2019 to 2022
$1.2M
Genetic regulation of stem cell behavior in planariansR15GM109372 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI OVIEDO, NESTOR J · 2014 to 2014
$352k
NIGMS NIH HHS R01 GM132753NIGMS NIH HHS R15 GM109372
6 · The paper itself

Abstract

Protein ADP-ribosylation is a reversible post-translational modification (PTM) process that plays fundamental roles in cell signaling. The covalent attachment of ADP ribose polymers is executed by PAR polymerases (PARP) and it is essential for chromatin organization, DNA repair, cell cycle, transcription, and replication, among other critical cellular events. The process of PARylation or polyADP-ribosylation is dynamic and takes place across many tissues undergoing renewal and repair, but the molecular mechanisms regulating this PTM remain mostly unknown. Here, we introduce the use of the planarian

Indexed as

AnimalsCell DeathDNA RepairGenomic InstabilityHelminth ProteinsHumansNeurogenesisPhylogenyPlanariansPoly(ADP-ribose) PolymerasesProtein Processing, Post-TranslationalRegenerationRNA, Double-StrandedRNA InterferenceSignal TransductionHelminth ProteinsPoly(ADP-ribose) PolymerasesRNA, Double-StrandedapoptosisneoblastsPARPplanariansregenerationstem cells

Identifiers

PMID32013251
PMCPMC7038108
OpenAlexW3003469360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.