Evidence map›Paper›PMID 32013245›Full record

ArticleSensors (Basel, Switzerland)2020

Quantitative 2D Magnetorelaxometry Imaging of Magnetic Nanoparticles using Optically Pumped Magnetometers.

Aaron Jaufenthaler, Peter Schier, Thomas Middelmann, Maik Liebl, Frank Wiekhorst, Daniel Baumgarten

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aaron JaufenthalerInstitute of Electrical and Biomedical Engineering, UMIT - Private University for Health Sciences, Medical Informatics and Technology, 6060 Hall in Tirol, Austria.ORCID 0000-0003-2352-7609
Peter SchierInstitute of Electrical and Biomedical Engineering, UMIT - Private University for Health Sciences, Medical Informatics and Technology, 6060 Hall in Tirol, Austria.
Thomas MiddelmannDepartment Biosignals, PTB - Physikalisch-Technische Bundesanstalt, 10587 Berlin, Germany.
Maik LieblDepartment Biosignals, PTB - Physikalisch-Technische Bundesanstalt, 10587 Berlin, Germany.
Frank WiekhorstDepartment Biosignals, PTB - Physikalisch-Technische Bundesanstalt, 10587 Berlin, Germany.
Daniel BaumgartenInstitute of Electrical and Biomedical Engineering, UMIT - Private University for Health Sciences, Medical Informatics and Technology, 6060 Hall in Tirol, Austria.

Funding

Deutsche Forschungsgemeinschaft BA4858/2-1Deutsche Forschungsgemeinschaft KO5321/3Deutsche Forschungsgemeinschaft TR408/11Deutsche Forschungsgemeinschaft WI4230/1-3Deutscher Akademischer Austauschdienst 57402032EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme 16NRM04
6 · The paper itself

Abstract

For biomagnetical applications exploiting physical properties of magnetic nanoparticles (MNP), e.g., magnetic hyperthermia, knowledge about the quantitative spatial MNP distribution is crucial, which can be extracted by magnetorelaxometry (MRX) imaging. In this paper, we present quantification, quantitative 1D reconstruction, and quantitative 2D imaging of MNP by exploiting optically pumped magnetometers for MRX. While highlighting the potential of commercially available optically pumped magnetometers (OPM) for MRXI, we discuss current limitations of the used OPM. We show, that with our OPM setup, MNP can be precisely quantified with iron amounts down to ≈ 6 g , which can be improved easily. With a 1D-reconstruction setup, point-like and complex MNP phantoms can be reconstructed quantitatively with high precision and accuracy. We show that with our developed 2D MRX imaging setup, which measures 12 c m by 8 c m , point-like MNP distributions with clinically relevant iron concentrations can be reconstructed precisely and accurately. Our 2D setup has the potential to be easily extended to a tomography styled (and thus slice-selective) 3D scanner, by adding a mechanical axis to the phantom.

Indexed as

magnetic nanoparticlesmagnetorelaxometry imagingoptically pumped magnetometers

Identifiers

PMID32013245
PMCPMC7038374

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.