Evidence map›Paper›PMID 32013200›Full record

ArticleMolecules (Basel, Switzerland)2020

The Possible Role of the Nitroso-Sulfide Signaling Pathway in the Vasomotoric Effect of Garlic Juice.

Andrea Berenyiova, Marian Grman, Anton Misak, Samuel Golas, Justina Cuchorova, Sona Cacanyiova

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Andrea BerenyiovaInstitute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences,841 04 Bratislava, Slovakia.
Marian GrmanInstitute for Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, 845 05 Bratislava, Slovakia.ORCID 0000-0003-2846-7924
Anton MisakInstitute for Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, 845 05 Bratislava, Slovakia.
Samuel GolasInstitute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences,841 04 Bratislava, Slovakia.
Justina CuchorovaAxxence Slovakia, Ltd., 811 07 Bratislava, Slovakia.
Sona CacanyiovaInstitute of Normal and Pathological Physiology, Centre of Experimental Medicine, Slovak Academy of Sciences,841 04 Bratislava, Slovakia.
Slovak Academy of Sciences · SKBiomedical Research Center of the Slovak Academy of Sciences · SKAxxence (Slovakia) · SK

Funding

Agentúra na Podporu Výskumu a Vývoja APVV-15-0565
6 · The paper itself

Abstract

The beneficial cardiovascular effects of garlic have been reported in numerous studies. The major bioactive properties of garlic are related to organic sulfides. This study aimed to investigate whether garlic juice works exclusively due to its sulfur compounds or rather via the formation of new products of the nitroso-sulfide signaling pathway. Changes in isometric tension were measured on the precontracted aortic rings of adult normotensive Wistar rats. We evaluated NO-donor (S-nitrosoglutathione, GSNO)-induced vasorelaxation and compare it with effects of hydrogen sulfide (H

Indexed as

GarlicSignal TransductionAnimalsAortaFruit and Vegetable JuicesHydrogen SulfideIn Vitro TechniquesIsometric ContractionMalePlant ExtractsRatsRats, WistarS-NitrosoglutathioneVasodilator AgentsHydrogen SulfidePlant ExtractsS-NitrosoglutathioneVasodilator AgentsgarlicH2S donorNO donorvasoactive mechanisms

Identifiers

PMID32013200
PMCPMC7038109
OpenAlexW3003358957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.