Evidence map›Paper›PMID 32013149›Full record

ArticleViruses2020

Imported Human West Nile Virus Lineage 2 Infection in Spain: Neurological and Gastrointestinal Complications.

María Velasco, María Paz Sánchez-Seco, Carolina Campelo, Fernando de Ory, Oriol Martin, Laura Herrero, Octavio J Salmerón Béliz, Teodora Minguito, Mª Carmen Campos, Francisca Molero and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. West Nile virus emergence in humans in Extremadura, Spain 2020.Frontiers in cellular and infection microbiology · 2023
    Article
  6. West Nile virus: another emerging arboviral risk for travelers?Current infectious disease reports · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

María VelascoHospital Universitario Fundación Alcorcón, 28922 Madrid, Spain.
María Paz Sánchez-SecoCentro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Madrid, Spain.ORCID 0000-0001-9033-7704
Carolina CampeloHospital Universitario Fundación Alcorcón, 28922 Madrid, Spain.
Fernando de OryCentro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Oriol MartinHospital Universitario Fundación Alcorcón, 28922 Madrid, Spain.
Laura HerreroCentro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Octavio J Salmerón BélizHospital Universitario Fundación Alcorcón, 28922 Madrid, Spain.
Teodora MinguitoCentro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Mª Carmen CamposHospital Universitario Fundación Alcorcón, 28922 Madrid, Spain.
Francisca MoleroCentro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Alejandro AlgoraHospital Universitario Fundación Alcorcón, 28922 Madrid, Spain.
Ana VázquezCentro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Hospital Universitario Fundación Alcorcón · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the first human case of West Nile virus (WNV) lineage 2 infection imported to Spain by a traveler returning from Romania. Serum, cerebrospinal fluid and urine samples were analyzed and West Nile virus infection was identified by PCR and serological tests. The patient developed fever, diarrhea and neurological symptoms, accompanied by mild pancreatitis, described previously in very few cases as a complication of WNV infection and by alithiasic cholecystitis. Viral RNA was detected in urine until 30 days after the onset of symptoms and neutralizing antibodies were detected at very low titers. The phylogenetic analysis in a fragment of the NS5 gene of the virus showed a homology with sequences from WNV lineage 2 belonging to the monophyletic Central/Southern European group.

Indexed as

Antibodies, NeutralizingAntibodies, ViralCommunicable Diseases, ImportedDisease OutbreaksGastrointestinal DiseasesHumansMaleMiddle AgedNervous System DiseasesPhylogenyRNA, ViralRomaniaSpainViral Nonstructural ProteinsWest Nile FeverWest Nile virusAntibodies, NeutralizingAntibodies, ViralNS5 protein, flavivirusRNA, ViralViral Nonstructural Proteinsdigestive complicationshumanneurological symptomsSpainWest Nile virus lineage 2

Identifiers

PMID32013149
PMCPMC7077332
OpenAlexW3003385867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.