Evidence map›Paper›PMID 32012740›Full record

ArticleInternational journal of molecular sciences2020

Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria.

Noriyuki Akahoshi, Tatsuro Minakawa, Masashi Miyashita, Uran Sugiyama, Chihiro Saito, Rintaro Takemoto, Akihiro Honda, Waka Kamichatani, Shotaro Kamata, Yasumi Anan and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Sulfide regulation and catabolism in health and disease.Signal transduction and targeted therapy · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Regulation of the redox metabolome and thiol proteome by hydrogen sulfide.Critical reviews in biochemistry and molecular biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Noriyuki AkahoshiDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Tatsuro MinakawaDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Masashi MiyashitaDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Uran SugiyamaDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Chihiro SaitoDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Rintaro TakemotoDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Akihiro HondaDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Waka KamichataniDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Shotaro KamataDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Yasumi AnanDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
Isao IshiiDepartment of Health Chemistry, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.ORCID 0000-0002-5367-205X
Showa Pharmaceutical University · JP

Funding

Ministry of Health, Labour and Welfare 16H05107Ministry of Health, Labour and Welfare 17K08287
6 · The paper itself

Abstract

Mercaptopyruvate sulfurtransferase (Mpst) and its homolog thiosulfate sulfurtransferase (Tst = rhodanese) detoxify cyanide to thiocyanate. Mpst is attracting attention as one of the four endogenous hydrogen sulfide (H

Indexed as

AllelesAmino Acid Metabolism, Inborn ErrorsAnimalsBiomarkersDisease Models, AnimalGene TargetingGenotypeLiverMiceMice, KnockoutMutationSulfhydryl CompoundsSulfurtransferasesbeta-mercaptolactateBiomarkersSulfhydryl CompoundsSulfurtransferasesCRISPR/Cas9cystathionine γ-lyasehydrogen sulfidemercaptolactate-cysteine disulfiduriamercaptopyruvate sulfurtransferasepassive systemic anaphylaxisreactive sulfur speciesthiosulfate sulfurtransferase

Identifiers

PMID32012740
PMCPMC7038117
OpenAlexW3001705385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.