Synthesis, Biological Assessment, and Structure Activity Relationship Studies of New Flavanones Embodying Chromene Moieties.

Eman Assirey, Azhaar Alsaggaf, Arshi Naqvi, Ziad Moussa, Rawda M Okasha, Tarek H Afifi, Alaa S Abd-El-Aziz

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

Chalcones as Emerging Antibacterial Scaffolds: A Mini Review.Mini reviews in medicinal chemistry · 2025
Review
In Vitro Approaches to Explore the Anticancer Potential of One Natural Flavanone and Four Derivatives Loaded in Biopolymeric Nanoparticles for Application in Topical Delivery Treatments.Pharmaceutics · 2023
Article
Design, Synthesis, Molecular Modeling, Anticancer Studies, and Density Functional Theory Calculations of 4-(1,2,4-Triazol-3-ylsulfanylmethyl)-1,2,3-triazole Derivatives.ACS omega · 2021
Article
2H/4H-Chromenes-A Versatile Biologically Attractive Scaffold.Frontiers in chemistry · 2020
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eman AssireyDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.

Azhaar AlsaggafDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.

Arshi NaqviDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.

Ziad MoussaDepartment of Chemistry, College of Science, United Arab Emirates University, 15551 Al Ain, UAE.

Rawda M OkashaDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.

Tarek H AfifiDepartment of Chemistry, Taibah University, Madinah 30002, Saudi Arabia.

Alaa S Abd-El-AzizDepartment of Chemistry, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island, PEI C1A 4P3, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel flavanones that incorporate chromene motifs are synthesized via a one-step multicomponent reaction. The structures of the new chromenes are elucidated by using IR,

Indexed as

Antineoplastic AgentsBenzopyransCell ProliferationDrug DesignDrug Screening Assays, AntitumorFlavanonesHumansMolecular Docking SimulationMolecular StructureNeoplasmsStructure-Activity RelationshipTumor Cells, CulturedAntineoplastic AgentsBenzopyransFlavanonesantimicrobial examinationcytotoxic behaviorflavanone-containing chromene motifsin-silico studiesmolecular modelingSAR analysis

Identifiers

PMID32012737

DOI10.3390/molecules25030544

PMCPMC7037824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.