Evidence map›Paper›PMID 32012701›Full record

ArticleJournal of clinical medicine2020

Activated Clotting Time Monitoring during Atrial Fibrillation Catheter Ablation: Does the Anticoagulant Matter?

Anne-Céline Martin, Maeva Kyheng, Vincent Foissaud, Alain Duhamel, Eloi Marijon, Sophie Susen, Anne Godier

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  4. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
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  14. Review
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  17. Activated Clotting Time Requires Adaptation Across Altered Measurement Devices: Determination of Appropriate Range During Atrial Fibrillation Ablation.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Anne-Céline MartinUniversité de Paris, Innovations Thérapeutiques en Hémostase, INSERM 1140, 4 avenue de l'observatoire, F-75006 Paris, France.
Maeva KyhengUniversity Lille, CHU Lille, EA 2694 - Santé publique: épidémiologie et qualité des soins, 1, place de Verdun, F-59000 Lille, France.
Vincent FoissaudHôpital d'Instruction des Armées Percy, Laboratoire de biologie, 101 avenue Henri Barbusse, F-92140 Clamart, France.
Alain DuhamelUniversity Lille, CHU Lille, EA 2694 - Santé publique: épidémiologie et qualité des soins, 1, place de Verdun, F-59000 Lille, France.
Eloi MarijonInserm UMR-S970, Université Paris Descartes, 56 Rue Leblanc, F-75015 Paris, France.
Sophie SusenInstitut d'Hématologie-transfusion, University Lille, CHU Lille, Boulevard du Pr Jules Leclercq, F-59037 Lille, France.
Anne GodierUniversité de Paris, Innovations Thérapeutiques en Hémostase, INSERM 1140, 4 avenue de l'observatoire, F-75006 Paris, France.
Université de Lille · FRInserm · FRDélégation Paris 5 · FRHôpital d'instruction des Armées Percy · FR

Funding

Société Française de Cardiologie 00000
6 · The paper itself

Abstract

Atrial fibrillation (AF) catheter ablation is performed in patients receiving direct oral anticoagulants (DOACs) with intra-procedural unfractionated heparin (UFH) administration to achieve activated clotting time (ACT) at 300 s, as for vitamin K antagonist (VKA). We determined whether ACT monitoring might be transposed from VKA to DOAC-treated patients. Blood was taken from 124 patients receiving uninterrupted dabigatran, rivaroxaban, apixaban, or VKA or being untreated. DOAC concentration or INR (VKA) were measured. ACT was determined at baseline, and after spiking with UFH doses equivalent to 1000, 2500, 5000 and 10000 IU

Indexed as

activated clotting timeatrial fibrillation catheter ablationdirect oral anticoagulantsoverdosingunfractionated heparin monitoring

Identifiers

PMID32012701
PMCPMC7074080
OpenAlexW3001573247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.