Evidence map›Paper›PMID 32012325›Full record

Observational studyHepatology (Baltimore, Md.)2020

Characterizing Hepatitis C Virus-Specific CD4

Felicity Hartnell, Ilaria Esposito, Leo Swadling, Anthony Brown, Chansavath Phetsouphanh, Catherine de Lara, Chiara Gentile, Bethany Turner, Lucy Dorrell, Stefania Capone and 3 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Hepatology (Baltimore, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Lymphocyte Landscape after ChronicInternational journal of molecular sciences · 2020
    Review
  12. Adaptive Immune Response against Hepatitis C Virus.International journal of molecular sciences · 2020
    Review
  13. Review
  14. Splenic CD4International journal of immunopathology and pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Felicity HartnellPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Ilaria EspositoPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Leo SwadlingPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Anthony BrownPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Chansavath PhetsouphanhPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Catherine de LaraPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Chiara GentileCEINGE-Advanced Biotechnologies, Naples, Italy.
Bethany TurnerJenner Vaccine Trials, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Lucy DorrellJenner Vaccine Trials, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Stefania CaponeReithera Srl, Rome, Italy.
Antonella FolgoriReithera Srl, Rome, Italy.
Eleanor BarnesPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Paul KlenermanPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Medawar Building for Pathogen Research · GBUniversity of Oxford · GBCeinge Biotecnologie Avanzate (Italy) · ITJohn Radcliffe Hospital · GB

Funding

Virology CoreU19AI082630 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG, GEORG Michael LAUER · 2009 to 2026
$48.1M
Department of Health NIHR Biomedical Research Centre (Oxford)Medical Research Council STOP-HCVMRF_ MRF-044-0001-RG-SWADLNIAID NIH HHS U19 AI082630NIH HHS NIAID U19AI082630Wellcome Trust 091663Wellcome Trust 109965Wellcome Trust 109965/Z/15/ZWellcome Trust WT109965MA
6 · The paper itself

Abstract

BACKGROUND AND

aimsInduction of functional helper CD4 APPROACH AND

resultsWe analyzed HCV-specific CD4

conclusionsHelper CD4

Indexed as

AdenoviridaeAntiviral AgentsCell LineDEAD-box RNA HelicasesFemaleGenetic VectorsHealthy VolunteersHepacivirusHepatitis C, ChronicHumansImmunogenicity, VaccineImmunologic MemoryMaleMiddle AgedNucleoside-TriphosphataseRemission, SpontaneousAntiviral AgentsDEAD-box RNA HelicasesNS3 protein, hepatitis C virusNucleoside-TriphosphataseSerine EndopeptidasesVaccines, SyntheticViral Hepatitis VaccinesViral Nonstructural ProteinsViral Proteases

Identifiers

PMID32012325
PMCPMC7610807
OpenAlexW3003214071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.