Evidence map›Paper›PMID 32012218›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2020

Trajectories of Frailty and Cognitive Decline Among Older Mexican Americans.

Bret T Howrey, Soham Al Snih, Joyce A Middleton, Kenneth J Ottenbacher

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bret T HowreyDepartment of Family Medicine, University of Texas Medical Branch, Galveston.
Soham Al SnihDivision of Rehabilitation Sciences, University of Texas Medical Branch, Galveston.
Joyce A MiddletonDivision of Physical Therapy, Medical University of South Carolina, Charleston.
Kenneth J OttenbacherDivision of Rehabilitation Sciences, University of Texas Medical Branch, Galveston.
The University of Texas Medical Branch at Galveston · USMedical University of South Carolina · US

Funding

Long-term Health Outcomes in Mexican American Older AdultsR01MD010355 · NIMHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI AL SNIH, SOHAM · 2016 to 2019
$1.9M
NIMHD NIH HHS R01 MD010355
6 · The paper itself

Abstract

backgroundProgressive physical frailty and cognitive decline in older adults is associated with increased risk of falls, disability, institutionalization, and mortality; however, there is considerable heterogeneity in progression over time. We identified heterogeneous frailty and cognitive decline trajectory groups and examined the specific contribution of health conditions to these trajectories among older Mexican origin adults.

methodsWe use a sample from the Hispanic Established Population for the Epidemiological Study of the Elderly (HEPESE) with at least two measures of frailty criteria during 18 years follow-up: slow gait, weak handgrip strength, exhaustion, and unexplained weight loss (n = 1362, mean age 72). Cognition was measured using the Mini-Mental State Examination (MMSE).

resultsUsing group-based trajectory models we identified three frailty groups-non-frail (n = 331), moderate progressive (n = 855), and progressive high (n = 149)-and three cognitive decline groups-non-cognitively impaired (476), moderate decline (677) and rapid decline (n = 209). The probability of membership in a high-frailty group given membership in a progressive cognitive decline group was 63%, while the probability of being in a non-frail group given membership in a non-cognitively impaired group was 68%. Predictors of membership into both the progressive high frailty and rapid cognitive decline groups combined were low education and diabetes. Weekly church attendance was associated with a 66% reduction in the odds of being in the combined groups.

conclusionsInterventions to reduce frailty rates and cognitive decline might focus on the management of underlying chronic disease and on increasing participation in activities outside the home.

Indexed as

Disease ProgressionAgedArthritisCognitive DysfunctionDiabetes MellitusEducational StatusFemaleFollow-Up StudiesFrailtyHumansHypertensionLeisure ActivitiesMaleMexican AmericansNeuropsychological TestsObesityHispanicPhysical functionTransition

Identifiers

PMID32012218
PMCPMC7357582
OpenAlexW3005276084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.