ArticlePLoS genetics2020
Parallel and nonparallel genomic responses contribute to herbicide resistance in Ipomoea purpurea, a common agricultural weed.
Article in PLoS genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 59 citations in OpenAlex.
- Target-gene overexpression and metabolic enhancement confer bentazone resistance in Amaranthus retroflexus.Pest management science · 2026Article
- Convergence and parallelism in the evolution of plant metabolism.Journal of integrative plant biology · 2026Review
- The genetic architecture and spatiotemporal dynamics of adaptation across human-modified landscapes.The New phytologist · 2026Review
- Recurrent mutations drive the rapid evolution of pesticide resistance in the two-spotted spider miteeLife · 2025Article
- Evaluation of herbicide formulations and spreading agents on survival of the bumblebee Bombus impatiens following spray and contact exposure.Ecotoxicology (London, England) · 2025Article
- Independently evolved pollution resistance in four killifish populations is largely explained by few variants of large effect.Evolutionary applications · 2024Article
- Yeast of Eden: microbial resistance to glyphosate from a yeast perspective.Current genetics · 2023Review
- A high diversity of non-target site resistance mechanisms to acetolactate-synthase (ALS) inhibiting herbicides has evolved within and among field populations of common ragweed (Ambrosia artemisiifolia L.).BMC plant biology · 2023Article
- Transcriptionally linked simultaneous overexpression of P450 genes for broad-spectrum herbicide resistance.Plant physiology · 2023Article
- Deep haplotype analyses of target-site resistance locus ACCase in blackgrass enabled by pool-based amplicon sequencing.Plant biotechnology journal · 2023Article
- The blackgrass genome reveals patterns of non-parallel evolution of polygenic herbicide resistance.The New phytologist · 2023Article
- Strong, Recent Selective Sweeps Reshape Genetic Diversity in Freshwater Bivalve Megalonaias nervosa.Molecular biology and evolution · 2023Article
- Reduced coenzyme Q synthesis confers non-target site resistance to the herbicide thaxtomin A.PLoS genetics · 2023Article
- Dissecting weed adaptation: Fitness and trait correlations in herbicide-resistant Alopecurus myosuroides.Pest management science · 2022Article
- Article
- Biotechnological Road Map for Innovative Weed Management.Frontiers in plant science · 2022Review
- Expression Pattern of Entire Cytochrome P450 Genes and Response of Defenses in a Metabolic-Herbicide-Resistant Biotype ofFrontiers in plant science · 2022Article
- Genomic-based epidemiology reveals independent origins and gene flow of glyphosate resistance in Bassia scoparia populations across North America.Molecular ecology · 2021Article
- Rapid Parallel Adaptation to Anthropogenic Heavy Metal Pollution.Molecular biology and evolution · 2021Article
- Parallel adaptation in autopolyploid Arabidopsis arenosa is dominated by repeated recruitment of shared alleles.Nature communications · 2021Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
The repeated evolution of herbicide resistance has been cited as an example of genetic parallelism, wherein separate species or genetic lineages utilize the same genetic solution in response to selection. However, most studies that investigate the genetic basis of herbicide resistance examine the potential for changes in the protein targeted by the herbicide rather than considering genome-wide changes. We used a population genomics screen and targeted exome re-sequencing to uncover the potential genetic basis of glyphosate resistance in the common morning glory, Ipomoea purpurea, and to determine if genetic parallelism underlies the repeated evolution of resistance across replicate resistant populations. We found no evidence for changes in 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), glyphosate's target protein, that were associated with resistance, and instead identified five genomic regions that showed evidence of selection. Within these regions, genes involved in herbicide detoxification-cytochrome P450s, ABC transporters, and glycosyltransferases-are enriched and exhibit signs of selective sweeps. One region under selection shows parallel changes across all assayed resistant populations whereas other regions exhibit signs of divergence. Thus, while it appears that the physiological mechanism of resistance in this species is likely the same among resistant populations, we find patterns of both similar and divergent selection across separate resistant populations at particular loci.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.