ArticleJMIR mHealth and uHealth2020
Feasibility and Health Benefits of an Individualized Physical Activity Intervention in Women With Metastatic Breast Cancer: Intervention Study.
Article in JMIR mHealth and uHealth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03148886 (Advanced Breast Cancer and Lifestyle Exercise Study), which is not on this map. Cited by 42 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Advanced Breast Cancer and Lifestyle Exercise Study
Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Using digital technology to support wellbeing and independence among people living with incurable cancers: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Promising Directions: A Systematic Review of Psychosocial and Behavioral Interventions with Cultural Incorporation for Advanced and Metastatic Cancer.International journal of behavioral medicine · 2024Pooled it
- Non-pharmacological interventions targeting mobility among people with advanced cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- mHealth Interventions to Address Physical Activity and Sedentary Behavior in Cancer Survivors: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Exercise effects on lean body mass, muscle strength and functional performance in patients with metastatic breast cancer: the randomized controlled PREFERABLE-EFFECT study.Breast cancer research : BCR · 2026Trial
- Feasibility and preliminary effects of the Fit2ThriveMB pilot physical activity promotion intervention on physical activity and patient reported outcomes in individuals with metastatic breast cancer.Breast cancer research and treatment · 2024Trial
- Machine Learning-Driven Phenogrouping and Cardiorespiratory Fitness Response in Metastatic Breast Cancer.JCO clinical cancer informatics · 2024Trial
- Empowering Rural Housewives in Iran: Utilizing the Transtheoretical Model to Increase Physical Activity.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024Trial
- Effects of the Fit2Thrive technology-supported physical activity promotion intervention components on sedentary behavior and light physical activity in breast cancer survivors.Journal of cancer survivorship : research and practice · 2026Article
- Monitoring Steps and Heart Rate Using a Withings Smartwatch in Children and Adolescents With Cancer: Validation Study.JMIR cancer · 2026Article
- Artificial intelligence for breast cancer management.Communications medicine · 2026Review
- Feasibility and Preliminary Efficacy of Aerobic Acute Exercise Prior to Immunotherapy and Chemotherapy Infusion in Patients with Metastatic Non-Small Cell Lung Cancer: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Outcomes for breast cancer survivors with metastatic disease in a physical activity program for medically underserved cancer survivors.Journal of cancer survivorship : research and practice · 2025Article
- Physical activity barriers, facilitators, and preferences in primary and tertiary prevention of breast cancer: a French national observational study.Journal of cancer survivorship : research and practice · 2025Article
- Health-related quality of life and physical activity collected via mobile application and wearable device in patients with HR +/HER2 - advanced breast cancer treated with palbociclib plus endocrine therapy or endocrine therapy alone: 6-month longitudinal study (JBCRG-26).Breast cancer (Tokyo, Japan) · 2025Observational
- Feasibility, Barriers, and Facilitators of Long-Term Physical Activity Tracking During Treatment: Interview Study Among Childhood Cancer Patients.JMIR pediatrics and parenting · 2025Article
- The role of virtual reality in breast cancer survivors: A scoping review.Preventive medicine reports · 2025Article
- Assessment of the functional and health-related needs of patients with metastatic breast cancer prior to initiation of cancer treatment.Breast cancer research and treatment · 2025Article
- Motivations and perceptions for physical activity in women living with metastatic breast cancer: a qualitative interview study.BMC cancer · 2025Article
- Acceptability of the Fit2ThriveMB mHealth physical activity promotion intervention in women with metastatic breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited knowledge regarding the potential benefits of physical activity in patients with metastatic breast cancer.
objectiveThe Advanced stage Breast cancer and Lifestyle Exercise (ABLE) Trial aimed to assess the feasibility of a physical activity intervention in women with metastatic breast cancer and to explore the effects of physical activity on functional, psychological, and clinical parameters.
methodsThe ABLE Trial was a single-arm, 6-month intervention study with a home-based, unsupervised, and personalized walking program using an activity tracker. At baseline and 6 months, we assessed anthropometrics, functional fitness, physical activity level, sedentary behavior, quality of life, fatigue, and tumor progression. Paired proportions were compared using the McNemar test and changes of parameters during the intervention were analyzed using the Wilcoxon signed-rank test, the Mann-Whitney test, and Spearman rank correlations.
resultsOverall, 49 participants (mean age 55 years; recruitment rate 94%) were enrolled and 96% adhered to the exercise prescription (attrition rate 2%). Statistically significant improvements in the 6-minute walking distance test (+7%, P<.001) and isometric quadriceps strength (+22%, P<.001), as well as decreases in body mass index (-2.5%, P=.03) and hip circumference (-4.0%, P<.001) were observed at 6 months. Quality of life remained stable and a nonstatistically significant decrease (-16%, P=.07) in fatigue was observed.
conclusionsThe high recruitment and adherence rates suggest the willingness of patients with metastatic breast cancer to participate in a physical activity program. The beneficial outcomes regarding physical fitness and anthropometry of this unsupervised physical activity program may encourage these patients to maintain a physically active lifestyle. Future randomized controlled trials with larger sample sizes are warranted.
trial registrationClinicalTrials.gov NCT03148886; https://clinicaltrials.gov/ct2/show/NCT03148886.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.