Evidence map›Paper›PMID 32011866›Full record

ArticleAnalytical chemistry2020

Rapid Characterization of Per- and Polyfluoroalkyl Substances (PFAS) by Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS).

James N Dodds, Zachary R Hopkins, Detlef R U Knappe, Erin S Baker

Abstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [Liquid Biopsy Revolutionizes the Precise Management of Tumors Across the Entire Course: Current Situation and Future Prospects].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Pooled it
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  10. The PFAS roadmap-Navigating a path together to improved management.Sustainability science and technology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James N DoddsDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.ORCID 0000-0002-9702-2294
Zachary R HopkinsDepartment of Civil, Construction, and Environmental Engineering, North Carolina State University, Raleigh, North Carolina 27696, United States.
Detlef R U KnappeDepartment of Civil, Construction, and Environmental Engineering, North Carolina State University, Raleigh, North Carolina 27696, United States.ORCID 0000-0003-1315-1791
Erin S BakerDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.ORCID 0000-0001-5246-2213

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Thomas Joseph McDonald · 2017 to 2026
$21.2M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Andrew R. Binder · 2015 to 2026
$18.3M
Uncovering the Mechanisms of PFAS-induced ImmunotoxicityP42ES031009 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI PLANCHART, ANTONIO J. · 2020 to 2024
$9.3M
NIEHS NIH HHS P30 ES025128NIEHS NIH HHS P42 ES027704NIEHS NIH HHS P42 ES031009
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) are an ensemble of persistent organic pollutants of global interest because of their associations with adverse health outcomes. Currently, environmental PFAS pollution is prolific as a result of the widespread manufacturing of these compounds and their chemical persistence. In this work, we demonstrate the advantages of adding ion mobility spectrometry (IMS) separation to existing LC-MS workflows for PFAS analysis. Using a commercially available drift tube IMS-MS, we characterized PFAS species and isomeric content in both analytical standards and environmental water samples. Molecular trendlines based on intrinsic mass and structural relationships were also explored for individual PFAS subclasses (

Indexed as

Hydrocarbons, FluorinatedIon Mobility SpectrometryMass SpectrometryMolecular StructurePolymersHydrocarbons, FluorinatedPolymers

Identifiers

PMID32011866
PMCPMC7173758

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.