ArticleBrain and behavior2020
Clinical features of right-to-left shunt in the different subgroups of migraine.
Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review and Meta-analysis of the Therapeutic Effect of Acupuncture on Migraine.Frontiers in neurology · 2020Pooled it
- Calcitonin gene-related peptide: a possible biomarker in migraine patients with patent foramen ovale.BMC neurology · 2024Article
- A three-classification model for identifying migraine with right-to-left shunt using lateralization of functional connectivity and brain network topology: a resting-state fMRI study.Frontiers in neuroscience · 2024Article
- Article
- Efficacy of contralateral acupuncture in women with migraine without aura: protocol for a randomised controlled trial.BMJ open · 2022Article
- Clinical features of right-to-left shunt in the different subgroups of migraine.Brain and behavior · 2020Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveSeveral investigations have documented an association between migraine and right-to-left shunt (RLS). However, whether there are specific clinical features that can distinguish between migraine patients with and without RLS is unclear. This study aims to explore whether there are specific clinical features that can distinguish between migraine patients with and without RLS, and to investigate the relationship between the degree of shunt and clinical parameters of headache.
methodsIn this study, we enrolled consecutive migraineurs who underwent a structured, standardized questionnaire for family and personal history and for detailed migraine features. RLS was diagnosed based on a contrast enhancement transcranial Doppler (c-TCD) examination.
resultsOverall, 113 migraine with aura (MA) and 192 migraine without aura (MO) patients were included. Patients with MA and RLS (MARLS+) had a higher frequency for sensory aura symptoms than those with MA without RLS (MARLS-) (27.4% vs. 10.0%, p = .03). Patients with MO and RLS (MORLS+) presented with significantly younger initial age of migraine onset and experienced more severe pain intensity than those with MO without RLS (MORLS-) (mean ± SD, 25.6 ± 8.9 vs. 29.8 ± 12.7 years, p = .008 and 5.9 ± 1.4 vs. 5.3 ± 1.3, p = .006, respectively). There was no relationship between the degree of shunt and the clinical parameters of headache.
conclusionsOur results indicate that MO patients presented with a younger initial age of migraine onset and that sensory aura symptoms in MA patients may predict the presence of RLS. However, we did not find support for relationship between the degree of shunt and clinical parameters of headache.
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