Evidence map›Paper›PMID 32011733›Full record

ArticleInternational journal of cancer2020

Theoretical potential for endometrial cancer prevention through primary risk factor modification: Estimates from the EPIC cohort.

Renée T Fortner, Anika Hüsing, Laure Dossus, Anne Tjønneland, Kim Overvad, Christina C Dahm, Patrick Arveux, Agnès Fournier, Marina Kvaskoff, Matthias B Schulze and 24 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Malignant Uterine Neoplasms Attended at a Brazilian Regional Hospital: 16-years Profile and Time Elapsed for Diagnosis and Treatment.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021
    Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 20 institutions in 9 countries.

Renée T FortnerDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-1426-8505
Anika HüsingDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Laure DossusNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Anne TjønnelandDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Kim OvervadDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Christina C DahmDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Patrick ArveuxCESP, Faculté de Médecine, Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Agnès FournierCESP, Faculté de Médecine, Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.
Marina KvaskoffCESP, Faculté de Médecine, Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France.ORCID 0000-0002-4557-3772
Matthias B SchulzeDepartment of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Manuela BergmannHuman Study Center, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Anna KarakatsaniHellenic Health Foundation, Athens, Greece.
Carlo La VecchiaHellenic Health Foundation, Athens, Greece.ORCID 0000-0003-1441-897X
Giovanna MasalaCancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network - ISPRO, Florence, Italy.
Valeria PalaEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Amalia MattielloDipartimento Di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy.
Rosario TuminoCancer Registry and Histopathology Department, Provincial Health Authority (ASP), Ragusa, Italy.
Fulvio RicceriDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.ORCID 0000-0001-8749-9737
Carla H van GilsJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Evelyn M MonninkhofJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Catalina BonetCatalan Institute of Oncology (ICO-IDIBELL)|Cancer Epidemiology Research Program, Unit of Nutrition and Cancer, L'Hospitalet de Llobregat, Barcelona, Spain.
José Ramón QuirósPublic Health Directorate, Asturias, Spain.
Maria-Jose SanchezAndalusian School of Public Health (EASP), Granada, Spain.
Daniel-Ángel Rodríguez-PalaciosDepartment of Epidemiology, Regional Health Council, Madrid, Spain.
Aurelio B GurreaCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Pilar AmianoCIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Naomi E AllenNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Ruth C TravisNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Marc J GunterNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Vivian ViallonNutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Elisabete WeiderpassInternational Agency for Research on Cancer (IARC), Lyon, France.ORCID 0000-0003-2237-0128
Elio RiboliDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Rudolf KaaksDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0003-3751-3929
Centre international de recherche sur le cancer · FRGerman Cancer Research Center · DERegional Health · USUniversité Paris-Sud · FRAarhus University · DKUniversity of Oxford · GBUtrecht University · NLBasque Government · ESFederico II University Hospital · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITGerman Institute of Human Nutrition · DEGobierno del Principado de Asturias · ESHellenic Health Foundation · GRImperial College London · GBInstitut d'Investigació Biomédica de Bellvitge · ESInstituto de Salud Pública de Navarra · ESNational and Kapodistrian University of Athens · GRPiedmont Reference Center for Epidemiology and Cancer Prevention · ITUniversidad de Granada · ESUniversity of Copenhagen · DK

Funding

Cancer Research UK 14136Cancer Research UK C570/A16491Cancer Research UK C8221/A19170Medical Research Council 1000143Medical Research Council G0401527Medical Research Council G1000143Medical Research Council MC‐UU_12015/1Medical Research Council MR/M012190/1Medical Research Council MR/N003284/1World Health Organization 001
6 · The paper itself

Abstract

Endometrial cancer (EC) incidence rates vary ~10-fold worldwide, in part due to variation in EC risk factor profiles. Using an EC risk model previously developed in the European EPIC cohort, we evaluated the prevention potential of modified EC risk factor patterns and whether differences in EC incidence between a European population and low-risk countries can be explained by differences in these patterns. Predicted EC incidence rates were estimated over 10 years of follow-up for the cohort before and after modifying risk factor profiles. Risk factors considered were: body mass index (BMI, kg/m

Indexed as

AdultAgedBody Mass IndexCohort StudiesContraceptives, OralEndometrial NeoplasmsEuropeFemaleHumansIncidenceMiddle AgedModels, StatisticalPrimary PreventionRisk FactorsContraceptives, Oralendometrial cancerprimary preventionrisk factors

Identifiers

PMID32011733
PMCPMC8611794
OpenAlexW3004462773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.