ArticleMedicine2020
Relationship between body mass index and arterial stiffness in a health assessment Chinese population.
Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 48 citations in OpenAlex.
- Longitudinal association between body weight change and brachial-ankle pulse wave velocity in patients with treated hypertension or diabetes mellitus: A post hoc analysis of the FMD-J study B.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Vascular Immune Remodeling: A CD4Aging cell · 2026Article
- Physical activity moderates the relationship between hot flashes and arterial wave reflection in perimenopausal females.Physiological reports · 2026Article
- The association between body composition and arterial stiffness: investigating the influence of inflammatory markers.Frontiers in cardiovascular medicine · 2026Article
- Pulse Wave Velocity Progression Determinants: No Significant Association with Novel Lipids Parameter.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Lean Mass Index, Not Body Mass Index, is Essentially Associated with Arterial Stiffness in Chinese Adults: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Risk prediction model of early vascular aging based on nomogram in patients with type 2 diabetes mellitus: a cross-sectional study in a Chinese population.Frontiers in medicine · 2025Article
- Proprotein convertase subtilisin/kexin type 9: a promising marker of cardiovascular risk in post-menopausal diabetic women in primary prevention.Frontiers in medicine · 2025Article
- U-shaped Association Between Weight-Adjusted-Waist Index and Arterial Stiffness Among Adult Hypertensive Patients: A Population-Based Study in the United States.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Arterial stiffness as a screening tool for cardiovascular risk in health and disease.Journal of family medicine and primary care · 2024Article
- Baroreflex Sensitivity as a Surrogate Biomarker for Concurrently Assessing the Severity of Arterial Stiffness and Cardiovascular Autonomic Neuropathy in Individuals with Type 2 Diabetes.Journal of personalized medicine · 2024Article
- Article
- Association of visceral fat area or BMI with arterial stiffness in ideal cardiovascular health metrics among T2DM patients.Journal of diabetes · 2024Article
- Association of body mass index with perioperative blood transfusion and short-term clinical outcomes in patients undergoing isolated coronary artery bypass grafting.BMC anesthesiology · 2023Article
- Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults.Metabolites · 2023Article
- Interaction between body mass index and blood pressure on the risk of vascular stiffness : A community-based cross-sectional study and implications for nursing.International journal of nursing sciences · 2023Article
- Evaluation of subclinical atherosclerosis in obese patients with three noninvasive methods: Arterial stiffness, carotid intima-media thickness, and biomarkers of endothelial dysfunction.Archives of endocrinology and metabolism · 2023Article
- Arterial Stiffness, Body Mass Index and Cardiovascular Disease Risk in Chinese Females at Various Ages.Reviews in cardiovascular medicine · 2023Article
- Association between blood glucose levels and arterial stiffness marker: comparing the second derivative of photoplethysmogram and cardio-ankle vascular index scores.Frontiers in endocrinology · 2023Article
- Improving Nutritional Status Was Associated with Decreasing Disease Severity and Shortening of Negative Conversion Time of PCR Test in Non-ICU Patients with COVID-19.Infection and drug resistance · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulse wave velocity (PWV) is a reliable measurement of arterial stiffness. Our study assesses the association between body mass index (BMI) and brachial-ankle PWV (baPWV) in a healthy cohort and seeks to explain possible mechanisms associated with the obesity paradox.A cross-sectional study was conducted in 578 normal individuals. The mean age was 48.3 ± 14.6 years, and 468 (81.0%) were men. 288 subjects (49.8%) were overweight and obese. baPWV and ankle-brachial index (ABI) were performed to evaluate arterial stiffness and atherosclerosis respectively. Normal weight was defined as 18.5 < BMI <25 kg/m, overweight as 25 ≤ BMI < 28 kg/m and obesity as BMI ≥28 kg/m.The overweight/obese subjects had significantly higher baPWV than the normal-weight group (1490.0 ± 308.0/1445.2 ± 245.2 cm/s vs 1371.2 ± 306.4 cm/s, P < .001). For the whole cohort, baPWV showed a significant positive correlation with BMI (r = 0.205, P < .001). However, baPWV was significantly lower as BMI increased: 1490.0 ± 308.0 cm/s (overweight); 1445.2 ± 245.2 cm/s (obese); P < .001) when adjusted for age, gender, heart rate, mean blood pressure, and cardiovascular risk factors (glucose, cholesterol, triglyceride, and low-density lipoprotein). For the whole cohort BMI was negatively associated with baPWV (β = -0.06, P = .042). ABI showed no relationship with BMI. In a middle-age healthy Chinese population, arterial stiffness measured as baPWV increased with BMI.Evidence of reduced arterial stiffness with increasing BMI when accounting for all other cardiovascular risk factors may contribute to underlying factors involved in the obesity paradox that becomes more prominent with increasing age.
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