Observational studyMedicine2020
Risk factors for gallstone disease in Shanghai: An observational study.
Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- A retrospective observational study: are gallstone patients aging, or are the elderly more susceptible to gallstones?BMC gastroenterology · 2026Observational
- Association between triglyceride glucose index-related indices with gallbladder disease: a prospective cohort study in rural China.Scientific reports · 2025Article
- Role of Radiation Therapy for Biliary Tract Cancers.Current oncology (Toronto, Ont.) · 2025Review
- Burden and risk factors for gallbladder and biliary tract diseases in China from 1990 to 2021 and burden predictions of risk factors for the next 15 years.Frontiers in medicine · 2025Article
- Long-term weight patterns and physical activity in gallstones.Scientific reports · 2024Article
- A Surgeon's Challenge: Diagnosing and Managing Hidden Bile Duct Stones Post-cholecystectomy.Cureus · 2024Article
- Article
- Liver Function-Related Indicators and Risk of Gallstone Diseases-A Multicenter Study and a Systematic Review and Meta-Analysis.Gastroenterology research and practice · 2024Article
- Different types and numbers metabolic abnormalities and risk of gallbladder stone disease in adults.Frontiers in nutrition · 2024Article
- Clinical correlation of cholelithiasis in patients undergoing percutaneous endoscopic gastrostomy.Scientific reports · 2023Article
- A clinician's guide to gallstones and common bile duct (CBD): A study protocol for a systematic review and evidence-based recommendations.Health science reports · 2023Article
- Age, gender, geographic and clinical differences for gallstones in China: a nationwide study.Annals of translational medicine · 2022Article
- Prevalence and Risk Factors of Gallbladder Stones and Polyps in Liaoning, China.Frontiers in medicine · 2022Article
- Acute Cholecystitis Presenting With Septic Shock as the First Presentation in an Elderly Patient.Cureus · 2022Article
- Association of apolipoprotein B XbaI (rs693) polymorphism and gallstone disease risk based on a comprehensive analysis.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021Article
- A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.Cellular and molecular gastroenterology and hepatology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to evaluate related risk factors for gallstone disease in Shanghai.We analyzed successive physical examinations of 2288 adults who were recruited at the Jinshan Branch of the Sixth People's Hospital of Shanghai and Jinshan Hospital Affiliated to Fudan University Hospital from July 2010 to December 2012. The odds ratios (ORs) with 95% confidence intervals (CIs) were used to measure the influence factors on the risks of gallstone development.The incidence of gallstone disease was 4.11% (94/2,288). Older age (OR: 1.02; 95% CI: 1.00-1.03; P = .039), higher body weight (OR: 1.02; 95% CI: 1.00-1.04; P = .021), alanine transaminase activity (ALT) (OR: 1.02; 95% CI: 1.01-1.03; P = .001), total standard bicarbonate (SB) (OR: 1.04; 95% CI: 1.02-1.06; P < .001), free SB (OR: 1.17; 95% CI: 1.12-1.21; P < .001), and low density lipoprotein (LDL) levels (OR: 1.59; 95% CI: 1.32-1.91; P < .001) were associated with an increased risk of gallstone disease. Based on univariate logistic analysis, increased triglyceride (TG) levels were associated with a reduced risk of gallstone disease (OR: 0.76; 95% CI: 0.60-0.97; P = .024). The results of multivariable logistic regression analysis showed higher LDL levels correlated with an increased risk of gallstone disease (OR: 1.92; 95% CI: 1.31-2.81; P < .001), while age, weight, ALT, total SB, free SB, and TG levels did not affect the risk of gallstone disease.The although unadjusted results showed age, weight, ALT, total SB, free SB, TG, and LDL levels to be associated with the risk of gallstone disease, adjusting for potential factors revealed only increased LDL levels to be associated with an increased risk of gallstone disease.
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