Evidence map›Paper›PMID 32011408›Full record

ArticleJournal of addiction medicine

Rapid Transition From Methadone to Buprenorphine Utilizing a Micro-dosing Protocol in the Outpatient Veteran Affairs Setting.

Joao P De Aquino, Christopher Fairgrieve, Sukhpreet Klaire, Gabriela Garcia-Vassallo

Abstract readCase Reports
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Emergency department management of opioid use disorder in pediatric patients.Journal of the American College of Emergency Physicians open · 2024
    Article
  6. Article
  7. Article
  8. Treating Chronic Pain with Buprenorphine-The Practical Guide.Current treatment options in oncology · 2021
    Review
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joao P De AquinoDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT (JPD, GG-V); U.S. Department of Veterans Affairs, VA Connecticut Healthcare System, West Haven, CT (JPD, GG-V); Center for Addiction and Mental Health, Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada (CF); British Columbia Centre on Substance Use and Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, BC, Canada (SK).
Christopher Fairgrieve
Sukhpreet Klaire
Gabriela Garcia-Vassallo

Funding

Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
NIDA NIH HHS R25 DA037756
6 · The paper itself

Abstract

objectivesAlternative transition protocols from methadone to buprenorphine in the treatment of opioid use disorder (OUD) are needed to reduce the risk of precipitated withdrawal and opioid use during induction.

methodsCase report (n = 1).

resultsOne patient with OUD underwent a rapid microinduction outpatient protocol that did not cause precipitated withdrawal or require preceding taper before cessation of methadone. The induction was carried out safely in the outpatient setting.

conclusionsThis report provides a patient-centered approach demonstrating feasibility and cost-effectiveness of rapid transition to buprenorphine in the US outpatient psychiatry setting. Barriers to adherence to opioid agonist therapy may be reduced using this protocol.

Indexed as

BuprenorphineOpioid-Related DisordersVeteransHumansMethadoneNarcotic AntagonistsOpiate Substitution TreatmentOutpatientsBuprenorphineMethadoneNarcotic Antagonists

Identifiers

PMID32011408
PMCPMC7392785

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.