Evidence map›Paper›PMID 32011244›Full record

ArticleIEEE transactions on bio-medical engineering2020

High-Resolution Dynamic

Bryan Clifford, Yuning Gu, Yuchi Liu, Kihwan Kim, Sherry Huang, Yudu Li, Fan Lam, Zhi-Pei Liang, Xin Yu

Open access · hybridAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  10. Genotype-driven therapeutic developments in Parkinson's disease.Molecular medicine (Cambridge, Mass.) · 2021
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bryan Clifford
Yuning Gu
Yuchi Liu
Kihwan Kim
Sherry Huang
Yudu Li
Fan Lam
Zhi-Pei Liang
Xin Yu
Case Western Reserve University · USUniversity of Illinois Urbana-Champaign · US

Funding

Phosphorus-31 MR Spectroscopic Imaging and FingerprintingR01EB023704 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI LIANG, ZHI-PEI, YU, XIN · 2017 to 2020
$1.8M
Ultra-high Resolution 3D MR Spectroscopic ImagingR21EB021013 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LIANG, ZHI-PEI · 2015 to 2016
$416k
NIBIB NIH HHS R01 EB023704NIBIB NIH HHS R21 EB021013
6 · The paper itself

Abstract

objectiveTo enable non-invasive dynamic metabolic mapping in rodent model studies of mitochondrial function using

methodsWe developed a novel method for high-resolution dynamic

resultsThe proposed method provided high-resolution dynamic metabolic mapping in rat hindlimb at spatial and temporal resolutions of 4[Formula: see text]2 mm

conclusionsA new model-based method is proposed to achieve high-resolution dynamic SIGNIFICANCE: Abnormal mitochondrial metabolism is a key cellular dysfunction in many prevalent diseases such as diabetes and heart disease; however, current understanding of mitochondrial function is mostly gained from studies on isolated mitochondria under nonphysiological conditions. The proposed method has the potential to open new avenues of research by allowing in vivo and longitudinal studies of mitochondrial dysfunction in disease development and progression.

Indexed as

AlgorithmsBrainAnimalsMagnetic Resonance ImagingMitochondriaRatsReproducibility of Results

Identifiers

PMID32011244
PMCPMC7384926
OpenAlexW3003165048

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.