Evidence map›Paper›PMID 32011030›Full record

ArticleInternational journal of geriatric psychiatry2020

Frailty as a predictor of mortality in older adults within 5 years of psychiatric admission.

Carolien E M Benraad, Miriam L Haaksma, Mieke H J Karlietis, Richard C Oude Voshaar, Jan Spijker, René J F Melis, Marcel G M Olde Rikkert

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Serum level of Vitamin D is associated with COVID-19 mortality rate in hospitalized patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolien E M BenraadDepartment of Geriatric Medicine/Radboudumc Alzheimer Centre, Donders Institute for Medical Neurosciences, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0001-9629-1452
Miriam L HaaksmaDepartment of Geriatric Medicine/Radboudumc Alzheimer Centre, Donders Institute for Medical Neurosciences, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0002-3518-9152
Mieke H J KarlietisDepartment of Geriatric Psychiatry, Pro Persona Mental Health Care, Nijmegen, The Netherlands.
Richard C Oude VoshaarDepartment of Psychiatry, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.
Jan SpijkerDepression Expertise Centre, Pro Persona Mental Health Care, Nijmegen, The Netherlands.
René J F MelisDepartment of Geriatric Medicine/Radboudumc Alzheimer Centre, Donders Institute for Medical Neurosciences, Radboud University Medical Centre, Nijmegen, The Netherlands.
Marcel G M Olde RikkertDepartment of Geriatric Medicine/Radboudumc Alzheimer Centre, Donders Institute for Medical Neurosciences, Radboud University Medical Centre, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOlder adults with psychiatric disorders have a substantially lower life expectancy than age-matched controls. Knowledge of risk factors may lead to targeting treatment and interventions to reduce this gap in life expectancy. In this study, we investigated whether frailty independently predicts mortality in older patients following an acute admission to a geriatric psychiatry hospital.

methodsClinical cohort study with a 5-year follow-up of 120 older patients admitted to a psychiatric hospital between February 2009 and September 2010. On admission, we assessed frailty with a frailty index (FI). We applied Cox regression analyses with time to death as the dependent variable, to examine whether the FI was a predictor for mortality, adjusted for age, sex, level of education, multimorbidity (Cumulative Illness Rating Scale for Geriatrics, CIRS-G scores), functional status (Barthel Index), neuropsychiatric symptoms (NPS), and severity of psychiatric symptoms at admission (Clinical Global Impressions Scale of Severity).

resultsOf the 120 patients, 63 (53%) patients were frail (FI ≥ 0.25), and 59 (49%) had died within 5 years. The FI predicted mortality with a hazard ratio (HR) of 1.78 (95% CI, 1.06-2.98) per 0.1 point increase, independent of the covariates. Co-morbidity measured by the CIRS-G and functional status measured by the Barthel Index were not significantly associated.

conclusionsFrailty was a strong predictor of mortality, independent of age, gender, multimorbidity, and functional status. This implies that frailty may be helpful in targeting inpatient psychiatric treatment and aftercare according to patients' life expectancy.

Indexed as

FrailtyAgedCohort StudiesFrail ElderlyGeriatric AssessmentHospitalizationHumansfrailtyfunctional statusgeriatric psychiatryhand grip strengthindexmortalitymultimorbiditynutritional statussevere psychiatric disorderswalking speed

Identifiers

PMID32011030
PMCPMC7317407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.