ArticleMagnetic resonance in medicine2020
Oscillating diffusion-encoding with a high gradient-amplitude and high slew-rate head-only gradient for human brain imaging.
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06606925 (Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training), which is not on this map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training
Who cites it
28 citing papers in PubMed.
- Complementary Sensitivity of Fixed-Time and Fixed-Oscillation Regimes to Exchange and Structural Disorder in the Human Brain Revealed Using Oscillating-Gradient Diffusion MRI With Ultra-Strong Gradients.Magnetic resonance in medicine · 2026Article
- Strong-Gradient Diffusion-Weighted Imaging of Prostate Cancer Using an Inside-Out Nonlinear Gradient Coil.Magnetic resonance in medicine · 2026Article
- Data-driven classification of tissue water populations by massively multidimensional diffusion-relaxation correlation MRI.Frontiers in neuroscience · 2026Article
- Enhanced spectral response in frequency-dependent diffusion measurements using a linear encoding model.Magnetic resonance in medicine · 2025Article
- Scattering approach to diffusion quantifies axonal damage in brain injury.Nature communications · 2025Article
- Oscillating gradient spin echo diffusion time effects implicate variations in neurite beading for the heterogeneous reduced diffusion in human acute ischemic stroke lesions.Magnetic resonance in medicine · 2025Article
- Comprehensive characterization of tumor therapeutic response via simultaneous mapping of cell size, density, and transcytolemmal water exchange.Magnetic resonance imaging · 2025Article
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- Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025Review
- Review
- Giving the prostate the boost it needs: Spiral diffusion MRI using a high-performance whole-body gradient system for high b-values at short echo times.Magnetic resonance in medicine · 2025Article
- Frequency-dependence in multidimensional diffusion-relaxation correlation MRI of the brain: Overfitting or meaningful parameter?Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Feasibility of brain intra-axonal microstructure imaging with ultrahigh B-encoding using MAGNUS ultra-high-performance gradients.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Restricted diffusion characteristics in oscillating gradient spin echo with mesoscopic phantom.Heliyon · 2024Article
- Human prostate MRI at ultrahigh-performance gradient: A feasibility study.Magnetic resonance in medicine · 2024Article
- Variability of multidimensional diffusion-relaxation MRI estimates in the human brain.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Article
- Military-related mild traumatic brain injury: clinical characteristics, advanced neuroimaging, and molecular mechanisms.Translational psychiatry · 2023Review
- Diffusion time dependency of extracellular diffusion.Magnetic resonance in medicine · 2023Article
- Improving MR cell size imaging by inclusion of transcytolemmal water exchange.NMR in biomedicine · 2022Article
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Authors and funding
11 authors.
Funding
Abstract
purposeWe investigate the importance of high gradient-amplitude and high slew-rate on oscillating gradient spin echo (OGSE) diffusion imaging for human brain imaging and evaluate human brain imaging with OGSE on the MAGNUS head-gradient insert (200 mT/m amplitude and 500 T/m/s slew rate).
methodsSimulations with cosine-modulated and trapezoidal-cosine OGSE at various gradient amplitudes and slew rates were performed. Six healthy subjects were imaged with the MAGNUS gradient at 3T with OGSE at frequencies up to 100 Hz and b = 450 s/mm
resultsSimulations show that to achieve high frequency and b-value simultaneously for OGSE, high gradient amplitude, high slew rates, and high peripheral nerve stimulation limits are required. A strong linear trend for increased diffusivity (mean: 8-19%, radial: 9-27%, parallel: 8-15%) was observed in normal white matter with OGSE (20 Hz to 100 Hz) as compared to PGSE. Linear fitting to frequency provided excellent correlation, and using a short-range disorder model provided radial long-term diffusivities of D
conclusionThe high gradient amplitude, high slew rate, and high peripheral nerve stimulation thresholds of the MAGNUS head-gradient enables OGSE acquisition for in vivo human brain imaging.
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