Evidence map›Paper›PMID 32010993›Full record

ArticleAmerican journal of hematology2020

Impact of minimal residual negativity using next generation flow cytometry on outcomes in light chain amyloidosis.

Surbhi Sidana, Eli Muchtar, M Hasib Sidiqi, Dragan Jevremovic, Angela Dispenzieri, Wilson Gonsalves, Francis Buadi, Martha Q Lacy, Suzanne R Hayman, Taxiarchis Kourelis and 8 more

Open access · greenAbstract read
In one paragraph

Article in American journal of hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Graded Cardiac Response Criteria for Patients With Systemic Light Chain Amyloidosis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  10. Article
  11. Article
  12. Biomarkers in AL Amyloidosis.International journal of molecular sciences · 2021
    Review
  13. Review
  14. Article
  15. Article
  16. Future Perspectives.Hematology/oncology clinics of North America · 2020
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 2 countries.

Surbhi SidanaDepartment of Medicine, Stanford University, Stanford, California.ORCID 0000-0003-3288-7614
Eli MuchtarDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
M Hasib SidiqiDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-1089-3853
Dragan JevremovicDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Angela DispenzieriDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-8780-9512
Wilson GonsalvesDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-6890-969X
Francis BuadiDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Martha Q LacyDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Suzanne R HaymanDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Taxiarchis KourelisDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-8573-9434
Prashant KapoorDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Ronald S GoDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Rahma WarsameDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-0240-0326
Nelson LeungDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-5651-1411
S Vincent RajkumarDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-5862-1833
Robert A KyleDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Morie A GertzDivision of Hematology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-3853-5196
Shaji K KumarDivision of Hematology, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · US

Funding

Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Amylou Constance Dueck · 2015 to 2026
$25.5M
NCI NIH HHS P50 CA186781
6 · The paper itself

Abstract

We evaluated bone marrow minimal residual disease (MRD) negativity in 44 patients with light chain (AL) amyloidosis using next generation flow cytometry (sensitivity ≥1 × 10

Indexed as

AgedFemaleFlow CytometryHumansImmunoglobulin Light-chain AmyloidosisMaleMiddle AgedNeoplasm, ResidualTreatment Outcome

Identifiers

PMID32010993
PMCPMC8019396
OpenAlexW3004928110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.