Evidence map›Paper›PMID 32010910›Full record

ArticleLab on a chip2020

Acoustic tweezers based on circular, slanted-finger interdigital transducers for dynamic manipulation of micro-objects.

Putong Kang, Zhenhua Tian, Shujie Yang, Wenzhuo Yu, Haodong Zhu, Hunter Bachman, Shuaiguo Zhao, Peiran Zhang, Zeyu Wang, Ruoyu Zhong and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Sonoporation: Past, Present, and Future.Advanced materials technologies · 2022
    Article
  4. Article
  5. Complex 3D bioprinting methods.APL bioengineering · 2021
    Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Putong KangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.ORCID 0000-0002-1762-1239
Zhenhua TianDepartment of Aerospace Engineering, Mississippi State University, Starkville, MS 39762, USA.
Shujie YangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.
Wenzhuo YuDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.
Haodong ZhuDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.
Hunter BachmanDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.ORCID 0000-0002-2356-5392
Shuaiguo ZhaoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.
Peiran ZhangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.
Zeyu WangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.
Ruoyu ZhongDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.ORCID 0000-0003-1205-3313
Duke University · USStark State College · US

Funding

Extracellular vesicles and their ncRNA cargo as markers of trophoblast injuryR01HD086325 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2015 to 2019
$3.6M
ExoSOUND: An Acoustofluidic Device for Exosome IsolationR44GM125439 · NIGMS · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2017 to 2018
$1.9M
Enabling Efficient, Fast, Biocompatible Exosome Separation via AcoustofluidicsR01GM132603 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2019 to 2022
$1.7M
Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platformR33CA223908 · NCI · NORTHEASTERN UNIVERSITY · PI EVENS, ANDREW M, HUANG, TONY JUN · 2018 to 2020
$1.2M
An integrated acoustofluidic droplet-sorting platform for classification of lymphocyte activity and functional phenotyping at single cell levelR01GM127714 · NIGMS · NORTHEASTERN UNIVERSITY · PI KONRY, TANIA TALI · 2018 to 2021
$1.2M
Acoustofluidic Separation (AFS), Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and BiofluidsUG3TR002978 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AN, JI YEONG, GALL, KENNETH A · 2019 to 2020
$823k
An Acoustofluidic Device for Biocompatible Platelet SeparationR43HL140800 · NHLBI · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2018 to 2018
$225k
NCATS NIH HHS UG3 TR002978NCI NIH HHS R33 CA223908NHLBI NIH HHS R43 HL140800NICHD NIH HHS R01 HD086325NIGMS NIH HHS R01 GM127714NIGMS NIH HHS R01 GM132603NIGMS NIH HHS R44 GM125439
6 · The paper itself

Abstract

Acoustic tweezing technologies are gaining significant attention from the scientific communities due to their versatility and biocompatibility. This study presents acoustic tweezers based on circular, slanted-finger interdigital transducers (CSFITs), which can steer the propagation direction of surface acoustic waves (SAWs) by tuning the excitation frequency. The CSFITs based acoustic tweezers enable dynamic and reconfigurable manipulation of micro-objects using multi-tone excitation signals. Compared to traditional interdigital transducers that generate and control SAWs along one axis, the CSFITs allow for simultaneously generating and independently controlling SAWs propagating along multiple axes by changing the frequency composition and the phase information in a multi-tone excitation signal. Moreover, the CSFITs based acoustic tweezers can be used for patterning cells/particles in various distributions and translating them along complex paths. We believe that our design is valuable for cellular-scale biological applications, in which on-chip, contactless, biocompatible handling of bioparticles is needed.

Indexed as

AcousticsSoundTransducers

Identifiers

PMID32010910
PMCPMC7182351
OpenAlexW3004225416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.