Evidence map›Paper›PMID 32010822›Full record

ArticleACS omega2020

Lipase-Catalyzed Transamidation of Urethane-Bond-Containing Ester.

Pia Skoczinski, Mónica K Espinoza Cangahuala, Dina Maniar, Katja Loos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pia SkoczinskiMacromolecular Chemistry and New Polymeric Materials, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Mónica K Espinoza CangahualaMacromolecular Chemistry and New Polymeric Materials, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Dina ManiarMacromolecular Chemistry and New Polymeric Materials, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Katja LoosMacromolecular Chemistry and New Polymeric Materials, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant improvement in mechanical properties and shape recovery in polyurethanes can be obtained by cross-linking, usually performed in a traditional chemical fashion. Here, we report model studies of enzymatic transamidations of urethane-bond-containing esters to study the principles of an enzymatic build-up of covalent cross-linked polyurethane networks via amide bond formation. The Lipase-catalyzed transamidation reaction of a urethane-bond-containing model ester ethyl 2-(hexylcarbamoyloxy)propanoate with various amines is discussed. A side product was formed, that could be successfully identified, and its synthesis reduced to a minimum (<1%). Furthermore, a noncatalyzed transamidation that is performed without CalB as the catalyst could be observed. Both observations are due to the known high reactivity of amines with urethane bonds.

Identifiers

PMID32010822
PMCPMC6990427

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.