ArticleScience advances2020
Shape-morphing living composites.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 89 citations in OpenAlex.
- Light-powered photosynthetic living actuator.Nature communications · 2026Article
- Polymer chemistry at the living-material interface.Chemical science · 2026Review
- Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- 3D Bioprinted Engineered Living Microreactors for Continuous Organophosphorus Compound Degradation.Small science · 2025Article
- Controlled Release of Microorganisms from Engineered Living Materials.ACS applied materials & interfaces · 2025Article
- A responsive living material prepared by diffusion reveals extracellular enzyme activity of cyanobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Shape and topology morphing of closed surfaces integrating origami and kirigami.Science advances · 2025Article
- Lighting up yeast: overview of optogenetics in yeast and their applications to yeast biotechnology.FEMS yeast research · 2025Review
- Strength in diversity: unlocking the full potential of engineered living materials with multistrain collaboration.FEMS microbiology reviews · 2025Review
- Shape-morphing of metastructures empowering locomotion.Nature materials · 2025Article
- Revolutionizing tumor diagnosis and treatment: the promise of DNA nanotechnology.Frontiers in immunology · 2025Review
- Mechanically Tunable, Compostable, Healable and Scalable Engineered Living Materials.Nature communications · 2024Article
- Transcriptional regulation of living materials via extracellular electron transfer.Nature chemical biology · 2024Article
- A yeast-malic acid crosslinker/polyacrylic acid hydrogel containing doxycycline for the treatment of periodontitis.RSC advances · 2024Article
- Harnessing Fungi Signaling in Living Composites.Global challenges (Hoboken, NJ) · 2024Article
- Biocomposite thermoplastic polyurethanes containing evolved bacterial spores as living fillers to facilitate polymer disintegration.Nature communications · 2024Article
- Ultrasensitive and robust mechanoluminescent living composites.Science advances · 2023Article
- Engineering living materials by synthetic biology.Biophysics reviews · 2023Review
- The complex structure ofScience advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
This work establishes a means to exploit genetic networks to create living synthetic composites that change shape in response to specific biochemical or physical stimuli. Baker's yeast embedded in a hydrogel forms a responsive material where cellular proliferation leads to a controllable increase in the composite volume of up to 400%. Genetic manipulation of the yeast enables composites where volume change on exposure to l-histidine is 14× higher than volume change when exposed to d-histidine or other amino acids. By encoding an optogenetic switch into the yeast, spatiotemporally controlled shape change is induced with pulses of dim blue light (2.7 mW/cm
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.