Evidence map›Paper›PMID 32010703›Full record

ArticleFrontiers in medicine2019

Role of Complex Networks for Integrating Medical Images and Radiomic Features of Intracranial Ependymoma Patients in Response to Proton Radiotherapy.

Marco Dominietto, Alessia Pica, Sairos Safai, Antony J Lomax, Damien C Weber, Enrico Capobianco

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Molecular Biology in Treatment Decision Processes-Neuro-Oncology Edition.International journal of molecular sciences · 2021
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Marco DominiettoCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Alessia PicaCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Sairos SafaiCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Antony J LomaxCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Damien C WeberCenter for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.
Enrico CapobiancoCenter for Computational Science, University of Miami, Coral Gables, FL, United States.
Paul Scherrer Institute · CHUniversity Hospital of Bern · CHUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cancers exhibit phenotypic diversity that medical imaging can precisely and non-invasively detect. Multiple factors underlying innovations and progresses in the medical imaging field exert diagnostic and therapeutic impacts. The emerging field of radiomics has shown unprecedented ability to use imaging information in guiding clinical decisions. To achieve clinical assessment that exploits radiomic knowledge sources, integration between diverse data types is required. A current gap is the accuracy with which radiomics aligns with clinical endpoints. We propose a novel methodological approach that synergizes data volumes (images), tissue-contextualized information breadth, and network-driven resolution depth. Following the Precision Medicine paradigm, disease monitoring and prognostic assessment are tackled at the individual level by examining medical images acquired from two patients affected by intracranial ependymoma (with and without relapse). The challenge of spatially characterizing intratumor heterogeneity is tackled by a network approach that presents two main advantages: (a) Increased detection in the image domain power from high spatial resolution, (b) Superior accuracy in generating hypotheses underlying clinical decisions.

Indexed as

ependymomamedical imagingnetwork inferenceprecision medicineradiomicstherapy response

Identifiers

PMID32010703
PMCPMC6978687
OpenAlexW3000063281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.