ArticleBiomedical optics express2020
Enhancement of diffuse correlation spectroscopy tissue blood flow measurement by acoustic radiation force.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Acoustomotive diffuse correlation spectroscopy for sensing mechanical stiffness in tissue-mimicking phantoms.Biomedical optics express · 2024Article
- Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques.Sensors (Basel, Switzerland) · 2023Review
- Portable, high speed blood flow measurements enabled by long wavelength, interferometric diffuse correlation spectroscopy (LW-iDCS).Scientific reports · 2023Article
- Acousto-Optics: Recent Studies and Medical Applications.Biosensors · 2023Review
- Characterization of continuous wave ultrasound for acousto-optic modulated diffuse correlation spectroscopy (AOM-DCS).Biomedical optics express · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current research on acousto-optic effects focuses on the interactions of acoustic waves with static optical properties rather than dynamic features such as tissue blood flow. Diffuse correlation spectroscopy (DCS) is an emerging technology capable of direct measurements of tissue blood flow by probing the movements of red blood cells (RBCs). In this article, we investigated the relations between the acoustic radiation force (ARF) and ultrasonic patterns by the finite element simulations. Based on the outcomes, we experimentally explored how the ultrasound-generated ARF enhance the DCS data as well as the blood flow measurements. The results yield the optimal pattern to generate ARF and elucidate the relations between the ultrasonic emission and flow elevations. The flow modality combing the DCS with ARF modulations, which was proposed in this study for the first time, would promote disease diagnosis and therapeutic assessment in the situation wherein the blood flow contrast between healthy and pathological tissues is insufficient.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.