Evidence map›Paper›PMID 32010516›Full record

ArticleBiomedical optics express2020

In vivo imaging of cervical precancer using a low-cost and easy-to-use confocal microendoscope.

Yubo Tang, Alex Kortum, Sonia G Parra, Imran Vohra, Andrea Milbourne, Preetha Ramalingam, Paul A Toscano, Kathleen M Schmeler, Rebecca R Richards-Kortum

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Cervical Cancer Screening Revolution: Advancements with Confocal Endomicroscopy.Asian Pacific journal of cancer prevention : APJCP · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Deep learning extended depth-of-field microscope for fast and slide-free histology.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yubo TangDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.ORCID https://orcid.org/0000-0003-2568-8940
Alex KortumDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Sonia G ParraDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Imran VohraDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Andrea MilbourneThe University of Texas MD Anderson Cancer Center, Department of Gynecologic Oncology and Reproductive Medicine, Houston, TX 77057, USA.
Preetha RamalingamThe University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, TX 77030, USA.
Paul A ToscanoThe University of Texas Health Science Center at Houston, School of Public Health, Brownsville, TX 78520, USA.
Kathleen M SchmelerThe University of Texas MD Anderson Cancer Center, Department of Gynecologic Oncology and Reproductive Medicine, Houston, TX 77057, USA.
Rebecca R Richards-KortumDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Rice University · USThe University of Texas MD Anderson Cancer Center · USThe University of Texas Health Science Center at Houston · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
High Resolution Imaging & HPV Oncoprotein Detection for Global Prevention of Cervical CancerR01CA186132 · NCI · RICE UNIVERSITY · PI RICHARDS-KORTUM, REBECCA R. · 2014 to 2018
$3.1M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA186132
6 · The paper itself

Abstract

Cervical cancer incidence and mortality rates remain high in medically underserved areas. In this study, we present a low-cost (<$5,000), portable and user-friendly confocal microendoscope, and we report on its clinical use to image precancerous lesions in the cervix. The confocal microendoscope employs digital apertures on a digital light projector and a CMOS sensor to implement line-scanning confocal imaging. Leveraging its versatile programmability, we describe an automated aperture alignment algorithm to ensure clinical ease-of-use and to facilitate technology dissemination in low-resource settings. Imaging performance is then evaluated in

Identifiers

PMID32010516
PMCPMC6968771
OpenAlexW2995455806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.