ArticleActa endocrinologica (Bucharest, Romania : 2005)
THE NEUROENDOCRINOLOGICAL ASPECTS OF PREGNANCY AND POSTPARTUM DEPRESSION.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Risk Factors for Postpartum Depression During COVID-19 Pandemic: A Systematic Literature Review.Journal of primary care & community healthPooled it
- The effect of antenatal common mental disorders on infant birth weight at the Dabat health and demographic surveillance site, Northwest Ethiopia: a community-based cohort study.BMC pregnancy and childbirth · 2026Article
- Advances in Perinatal Depression: A Focus on Screening and Treatment.Journal of clinical medicine · 2026Review
- ADHD and the female reproductive stages: menstruation, perinatal and menopause.Archives of women's mental health · 2026Article
- Exploring sources of social support during pregnancy- a qualitative study in rural southern India.BMC pregnancy and childbirth · 2026Article
- Pregnant Women's Experiences and Perceptions of the Impact of Exercise on Mental Health During Pregnancy-A Qualitative Study.Healthcare (Basel, Switzerland) · 2026Article
- Association of depressive and/or pregnancy-related anxiety symptoms in pregnancy with maternal and neonatal biologic aging.BMC pregnancy and childbirth · 2026Article
- Preeclampsia as an Independent and Major Risk Factor for Significant Postpartum Depression Symptomatology: Results from a Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Postnatal Common Mental Disorders and Their Predictors in Northwest Ethiopia: A Community-Based Cohort Study.Depression and anxiety · 2026Article
- Postpartum Mental Health Problems in the Mothers of Very, Moderately and Late Preterm Infants During and After COVID-19 Pandemic: A Cross-Sectional Comparison Study and Possible Risk Factors.Depression and anxiety · 2026Article
- A Case-Crossover Study of Extreme Heat and Psychiatric Emergency Encounters Among Vulnerable Pregnant People.Paediatric and perinatal epidemiology · 2025Article
- Postpartum Depression and the Disclosure Process.The Journal of perinatal education · 2025Article
- Effect of nanocurcumin administration on superoxide dismutase and progesterone level exposure to noise stress during pregnancy in mice.Open veterinary journal · 2025Article
- Australian Women in the Perinatal Period During COVID-19: The Influence of Self-Compassion and Emotional Regulation on Anxiety, Depression, and Social Anxiety.Healthcare (Basel, Switzerland) · 2025Article
- Awareness of postpartum depression among midwives and pregnant women in Arkhangelsk, Arctic Russia.Global health action · 2024Article
- COVID-19 Public Health Restrictions and New Mothers' Mental Health: A Qualitative Scoping Review.Qualitative health research · 2024Article
- The Potential Health Risks and Benefits of Progesterone in the Transgender Woman Population-A Narrative Review.Journal of clinical medicine · 2024Review
- Partnership quality and maternal depressive symptoms in the transition to parenthood: a prospective cohort study.BMC pregnancy and childbirth · 2024Article
- Postpartum Depression: Etiology, Treatment, and Consequences for Maternal Care.Diagnostics (Basel, Switzerland) · 2024Review
- The psychosocial experiences of pregnant women in the early stages of the COVID-19 pandemic: A retrospective qualitative study.PloS one · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTies between the endocrine system and mental health are undeniably a consistent point of interest in modern day medicine. Furthermore, mental disturbances due to hormonal changes following childbirth have been mentioned in medical literature since Hippocrates. Considering the dramatic endocrine, paracrine and autocrine changes that occur during gestation, labour and postnatal phase, hormonal theories are not to be ignored in the treatment of postpartum disorders.
resultsReproductive hormones are known to modulate behavioural, emotional and cognitive response, therefore rapid changes in estradiol and progesterone plasma concentrations during pregnancy and labour create a vulnerable terrain leading towards postpartum disorders. New research shows that women suffering from postpartum disorders have abnormal neural responses, suggesting a neuroendocrine explanation for postpartum syndromes.
conclusionTo facilitate further research in this area, we present new information on several hormonal interactions and the psychiatric response involved in pregnancy and labour, offering an interdisciplinary outlook on pregnancy and postpartum disorders. There is enough evidence to suggest that estradiol, progesterone, oxytocin, cortisol and thyroid hormones are some of many hormones involved in postpartum syndromes and tackling their perinatal imbalance with pharmacological substituents or antagonists could be useful as an adjuvant form of treatment in future patients.
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