Evidence map›Paper›PMID 32010148›Full record

ArticleFrontiers in immunology2019

Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location.

Jana Sarkander, Shintaro Hojyo, Mathias Mursell, Yuzuru Yamasaki, Tsung-Yen Wu, Damon J Tumes, Kosuke Miyauchi, Cam Loan Tran, Jinfang Zhu, Max Löhning and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jana SarkanderDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Shintaro HojyoDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Mathias MursellDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Yuzuru YamasakiDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Tsung-Yen WuDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Damon J TumesCentre for Cancer Biology, SA Pathology and The University of South Australia, Adelaide, SA, Australia.
Kosuke MiyauchiLaboratory for Cytokine Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Cam Loan TranDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Jinfang ZhuLaboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Max LöhningDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Andreas HutloffDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Mir-Farzin MashreghiDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Masato KuboLaboratory for Cytokine Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Andreas RadbruchDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.
Koji TokoyodaDeutsches Rheuma-Forschungszentrum Berlin, Leibniz Institute, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4 T cell memory is fundamental for long-lasting immunity and effective secondary responses following infection or vaccination. We have previously found that memory CD4 T cells specific for systemic antigens preferentially reside in the bone marrow (BM) and arise from splenic CD49b

Indexed as

Immunologic MemoryAnimalsBone MarrowCD28 AntigensCD4-Positive T-LymphocytesCell DivisionCell MovementIntegrin alpha2Interleukin-2Interleukin-2 Receptor beta SubunitMiceMice, KnockoutReceptors, CCR7T-bet Transcription FactorT-Box Domain ProteinsCcr7 protein, mouseCD28 AntigensIl2rb protein, mouseIntegrin alpha2Interleukin-2Interleukin-2 Receptor beta SubunitReceptors, CCR7T-bet Transcription FactorT-Box Domain Proteinsbone marrowCD4 T cellscell divisionmemorymigration

Identifiers

PMID32010148
PMCPMC6974474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.