Evidence map›Paper›PMID 32010130›Full record

ReviewFrontiers in immunology2019

Exploiting Human NK Cells in Tumor Therapy.

Paola Vacca, Gabriella Pietra, Nicola Tumino, Enrico Munari, Maria Cristina Mingari, Lorenzo Moretta

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Cell therapy in pediatric blood diseases.Frontiers in medicine · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Natural killer cells: a promising immunotherapy for cancer.Journal of translational medicine · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Paola VaccaImmunology Research Area, IRCCS Bambino Gesù Pediatric Hospital, Rome, Italy.
Gabriella PietraUOC Immunology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Nicola TuminoImmunology Research Area, IRCCS Bambino Gesù Pediatric Hospital, Rome, Italy.
Enrico MunariDepartment of Pathology, IRCCS Sacro Cuore Don Calabria, Negrar, Italy.
Maria Cristina MingariUOC Immunology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Lorenzo MorettaImmunology Research Area, IRCCS Bambino Gesù Pediatric Hospital, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITOspedale Policlinico San Martino · ITBambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NK cells play an important role in the innate defenses against tumor growth and metastases. Human NK cell activation and function are regulated by an array of HLA class I-specific inhibitory receptors and activating receptors recognizing ligands expressed

Indexed as

AnimalsCTLA-4 AntigenHistocompatibility Antigens Class IHumansImmunotherapyKiller Cells, NaturalNeoplasmsT-LymphocytesCTLA-4 AntigenHistocompatibility Antigens Class Ianti-tumor therapyimmunotherapyinhibitory checkpointsinnate immunityNK cells

Identifiers

PMID32010130
PMCPMC6978749
OpenAlexW3000328972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.