Evidence map›Paper›PMID 32009951›Full record

ArticleFrontiers in pharmacology2019

DeepMalaria: Artificial Intelligence Driven Discovery of Potent Antiplasmodials.

Arash Keshavarzi Arshadi, Milad Salem, Jennifer Collins, Jiann Shiun Yuan, Debopam Chakrabarti

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  15. Molecular Descriptors Property Prediction Using Transformer-Based Approach.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arash Keshavarzi ArshadiBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States.
Milad SalemDepartment of Electrical and Computer Engineering, University of Central Florida, Orlando, FL, United States.
Jennifer CollinsBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States.
Jiann Shiun YuanDepartment of Electrical and Computer Engineering, University of Central Florida, Orlando, FL, United States.
Debopam ChakrabartiBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimalarial drugs are becoming less effective due to the emergence of drug resistance. Resistance has been reported for all available malaria drugs, including artemisinin, thus creating a perpetual need for alternative drug candidates. The traditional drug discovery approach of high throughput screening (HTS) of large compound libraries for identification of new drug leads is time-consuming and resource intensive. While virtual

Indexed as

artificial intelligencedeep learningdrug discoveryinhibitionmalariatoxicityvirtual screening

Identifiers

PMID32009951
PMCPMC6974622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.