Evidence map›Paper›PMID 32009524›Full record

Observational studyJournal of the American Heart Association2020

Safety and Utility of Cardiopulmonary Exercise Testing in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia.

Paul J Scheel, Roberta Florido, Steven Hsu, Brittney Murray, Crystal Tichnell, Cynthia A James, Julia Agafonova, Harikrishna Tandri, Daniel P Judge, Stuart D Russell and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Safety of Exercise Testing in the Clinical Chinese Population.Frontiers in cardiovascular medicine · 2021
    Article
  12. Review
  13. Risk stratification in cardiomyopathy.European journal of preventive cardiology · 2020
    Review
  14. Observational
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Paul J ScheelDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Roberta FloridoDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Steven HsuDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Brittney MurrayDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Crystal TichnellDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Cynthia A JamesDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Julia AgafonovaDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Harikrishna TandriDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Daniel P JudgeDivision of Cardiology Department of Medicine Medical University of South Carolina Charleston SC.
Stuart D RussellDivision of Cardiology Department of Medicine Duke University School of Medicine Durham NC.
Ryan J TedfordDivision of Cardiology Department of Medicine Medical University of South Carolina Charleston SC.
Hugh CalkinsDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Nisha A GilotraDivision of Cardiology Department of Medicine The Johns Hopkins Hospital Baltimore MD.
Johns Hopkins Hospital · USMedical University of South Carolina · USDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is characterized by high arrhythmic burden and progressive heart failure, which can prompt referral for heart transplantation. Cardiopulmonary exercise testing (CPET) has an established role in risk stratification for advanced heart failure therapies, but has not been described in ARVC/D. This study sought to determine the safety and prognostic utility of CPET in patients with ARVC/D. Methods and Results Using the Johns Hopkins ARVC/D Registry, we examined patients with ARVC/D undergoing CPET. Baseline characteristics and transplant-free survival were compared on the basis of peak oxygen consumption (pVO2) (≤14 or >14 mL/kg per minute) and ventilatory efficiency (Ve/VCO

Indexed as

Exercise TestExercise ToleranceOxygen ConsumptionAdolescentAdultArrhythmogenic Right Ventricular DysplasiaFemaleHeart FailureHeart TransplantationHumansMaleMiddle AgedPredictive Value of TestsProgression-Free SurvivalRegistriesRetrospective Studiesarrhythmiascardiomyopathyexercise testinggeneticsheart failuretransplantation

Identifiers

PMID32009524
PMCPMC7033873
OpenAlexW3004538398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.