Evidence map›Paper›PMID 32009518›Full record

ArticleRNA biology2020

RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs for discerning baseline expression exclusivity of candidate biomarkers.

Pierre R Bushel, Florian Caiment, Han Wu, Raegan O'Lone, Frank Day, John Calley, Aaron Smith, Jianying Li, Alison H Harrill

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Rapidly Evolving X-linkedbioRxiv : the preprint server for biology · 2024
    Article
  5. MicroRNAs as Biomarkers for Ionizing Radiation Injury.Frontiers in cell and developmental biology · 2022
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Pierre R BushelBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, USA.ORCID 0000-0001-5188-8693
Florian CaimentDepartment of Toxicogenomics, Maastricht University, Maastricht, The Netherlands.
Han WuDepartment of Discovery and Development Statistics, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN, USA.
Raegan O'LoneeSTAR, Health and Environmental Sciences Institute, Washington, DC, USA.
Frank DayOffice of Scientific Computing, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, USA.
John CalleyDepartment of TTX Bioinformatics, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN, USA.
Aaron SmithDepartment of Investigative Toxicology, Non-Clinical Safety Assessment and Pathology, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN, USA.
Jianying LiMicroarray and Genome Informatics Group, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, USA.
Alison H HarrillDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, USA.
Eli Lilly (United States) · USNational Institute of Environmental Health Sciences · USHealth and Environmental Sciences Institute · USMaastricht University · NLTriangle · US

Funding

Microarray and Genome InformaticsZIAES102345 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BUSHEL, ROBERT · 2009 to 2021
$10.8M
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small RNAs that regulate mRNA expression and have been targeted as biomarkers of organ damage and disease. To explore the utility of miRNAs to assess injury to specific tissues, a tissue atlas of miRNA abundance was constructed. The

Indexed as

AnimalsBiomarkersComputational BiologyFemaleGene Expression ProfilingGene Expression RegulationHumansMaleMicroRNAsOrgan SpecificityRatsRNA InterferenceBiomarkersMicroRNAsbiomarkermicroRNAmiRNA expressionorgan-specificRATEmiRsRNA-Seqtissue-enrichedtissue-specific

Identifiers

PMID32009518
PMCPMC7237151
OpenAlexW3004607607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.