Evidence map›Paper›PMID 32009319›Full record

ReviewAllergy, asthma & immunology research2020

Chinese Society of Allergy and Chinese Society of Otorhinolaryngology-Head and Neck Surgery Guideline for Chronic Rhinosinusitis.

Zheng Liu, Jianjun Chen, Lei Cheng, Huabin Li, Shixi Liu, Hongfei Lou, Jianbo Shi, Ying Sun, Dehui Wang, Chengshuo Wang and 30 more

Open access · diamondAbstract readReview
In one paragraph

Review in Allergy, asthma & immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Comprehensive immunological and molecular analysis revealed inflammation-related diagnostic signatures in chronic rhinosinusitis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  7. Short-term effectiveness of tezepelumab on ENT manifestations in patients undergoing treatment for severe asthma: A pilot real-life study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Observational
  8. Article
  9. Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024).World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  10. Morphological Sinus Features and Chronic Rhinosinusitis Risk: A Radiomics Study.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  11. Article
  12. Article
  13. Prognostic value of preoperative CCL26 serum levels in the surgical treatment of chronic rhinosinusitis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  14. Article
  15. Article
  16. IL-8 promotes pyroptosis through ERK pathway and mediates glucocorticoid resistance in chronic rhinosinusitis with nasal polyps.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  17. Review
  18. Article
  19. Review
  20. The Effects of Mepolizumab on CRSwNP: Real-Life Evidence.Journal of personalized medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 12 institutions in 1 country.

Zheng Liu *Department of Otolaryngology Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-4168-6702
Jianjun Chen *Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-8631-4558
Lei Cheng *Department of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0001-6541-7702
Huabin Li *Department of Otolaryngology, Head and Neck Surgery, Affiliated Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-2477-2879
Shixi Liu *Department of Otolaryngology, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0003-4083-6737
Hongfei Lou *Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-8553-812X
Jianbo Shi *Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-7733-8833
Ying Sun *Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.ORCID 0000-0003-4052-2498
Dehui Wang *Department of Otolaryngology, Head and Neck Surgery, Affiliated Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.ORCID 0000-0003-0346-3193
Chengshuo Wang *Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-0646-5135
Xiangdong Wang *Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.ORCID 0000-0002-0409-322X
Yongxiang Wei *Department of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-4779-5491
Weiping Wen *Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-1075-7475
Pingchang Yang *Research Center of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China.ORCID 0000-0002-6806-9464
Qintai Yang *Department of Otolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0000-0003-3377-737X
Gehua Zhang *Department of Otolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-1917-0283
Yuan Zhang *Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-1080-4267
Changqing Zhao *Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Shanxi Medical University, Taiyuan, China.ORCID 0000-0002-3825-0940
Dongdong Zhu *Department of Otolaryngology Head and Neck Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.ORCID 0000-0002-8495-5626
Li Zhu *Department of Otolaryngology Head and Neck Surgery, Peking University Third Hospital, Beijing, China.ORCID 0000-0002-5988-5371
Fenghong ChenOtorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-8015-3282
Yi DongBeijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.ORCID 0000-0001-6864-4724
Qingling FuOtorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-5969-628X
Jingyun LiBeijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.ORCID 0000-0001-8066-4648
Yanqing LiDepartment of Otolaryngology, Head and Neck Surgery, Affiliated Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.ORCID 0000-0001-5574-7994
Chengyao LiuDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0056-9032
Feng LiuDepartment of Otolaryngology, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0003-2866-2340
Meiping LuDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0001-8097-614X
Yifan MengDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-2988-8763
Jichao ShaDepartment of Otolaryngology Head and Neck Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.ORCID 0000-0002-3731-3954
Wenyu SheBeijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.ORCID 0000-0001-5632-3552
Lili ShiDepartment of Otolaryngology Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-1923-2616
Kuiji WangDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0052-6278
Jinmei XueDepartment of Otolaryngology Head and Neck Surgery, The Second Hospital, Shanxi Medical University, Taiyuan, China.ORCID 0000-0002-7428-7812
Luoying YangDepartment of Otolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-5061-9192
Min YinDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.ORCID 0000-0002-6297-0016
Lichuan ZhangDepartment of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-5398-0557
Ming ZhengDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-8991-6642
Bing ZhouDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China. entzhou@263.net.ORCID 0000-0003-2640-7370
Luo ZhangDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0910-9884
Beijing Tongren Hospital · CNSun Yat-sen University · CNBeijing Institute of Neurosurgery · CNEye & ENT Hospital of Fudan University · CNNanjing Medical University · CNUnion Hospital · CNCapital Medical University · CNShanxi Medical University · CNSichuan University · CNTongji Hospital · CNPeking University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current document is based on a consensus reached by a panel of experts from the Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck Surgery, Rhinology Group. Chronic rhinosinusitis (CRS) affects approximately 8% of Chinese adults. The inflammatory and remodeling mechanisms of CRS in the Chinese population differ from those observed in the populations of European descent. Recently, precision medicine has been used to treat inflammation by targeting key biomarkers that are involved in the process. However, there are no CRS guidelines or a consensus available from China that can be shared with the international academia. The guidelines presented in this paper cover the epidemiology, economic burden, genetics and epigenetics, mechanisms, phenotypes and endotypes, diagnosis and differential diagnosis, management, and the current status of CRS in China. These guidelines-with a focus on China-will improve the abilities of clinical and medical staff during the treatment of CRS. Additionally, they will help international agencies in improving the verification of CRS endotypes, mapping of eosinophilic shifts, the identification of suitable biomarkers for endotyping, and predicting responses to therapies. In conclusion, these guidelines will help select therapies, such as pharmacotherapy, surgical approaches and innovative biotherapeutics, which are tailored to each of the individual CRS endotypes.

Indexed as

biomarkersChinaChronic, sinusitisdiagnosisendotypesepigenesisguidelineinflammationmanagementphenotype

Identifiers

PMID32009319
PMCPMC6997287
OpenAlexW3003472019

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.