ArticleTransboundary and emerging diseases2020
Genetic characterization of canine parvovirus type 2c from domestic dogs in Korea.
Article in Transboundary and emerging diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- Molecular Characteristics and Genetic Diversity of Canine Parvovirus in Shanghai, China, from 2016 to 2025.Microorganisms · 2026Article
- Clinicopathological profiling of diarrheic canine parvovirus-circovirus co-infections in Hanoi, Vietnam.Open veterinary journal · 2026Article
- Epidemiological status and genome characteristics of canine parvovirus in China from 2022 to 2024.Archives of virology · 2025Article
- Detection and molecular epidemiology of canine parvovirus and identification of highly pathogenic CPV-2c isolates from Shandong, China.Virus genes · 2025Article
- First Identification of CPV-2c Infection in a Wild Cub Giant Panda (Transboundary and emerging diseases · 2025Article
- Canine parvovirus in North-East India: a phylogenetic and evolutionary analysis.The veterinary quarterly · 2024Article
- Genetic Diversity and Recombination Analysis of Canine Parvoviruses Prevalent in Central and Eastern China, from 2020 to 2023.Microorganisms · 2024Article
- Whole-genome sequence analysis of canine parvovirus reveals replacement with a novel CPV-2c strain throughout India.Archives of virology · 2024Article
- Detection of Selected Canine Viruses in Nigerian Free-Ranging Dogs Traded for Meat Consumption.Animals : an open access journal from MDPI · 2023Article
- Prevalence and Characteristics of Canine Parvovirus Type 2 in Henan Province, China.Microbiology spectrum · 2022Article
- Genetic characterization and evolutionary analysis of canine parvovirus in Tangshan, China.Archives of virology · 2022Article
- Molecular characteristics and genetic evolutionary analyses of circulating parvoviruses derived from cats in Beijing.BMC veterinary research · 2022Article
- Characterization of the VP2 and NS1 genes from canine parvovirus type 2 (CPV-2) and feline panleukopenia virus (FPV) in Northern China.Frontiers in veterinary science · 2022Article
- Identification of novel recombinants and proposed standard reference genomes for phylogenetic classification of canine parvovirus-2 (CPV-2): Comprehensive analysis revealing global evolutionary trait.Frontiers in veterinary science · 2022Article
- Isolation and identification of a novel canine parvovirus type 2c strain in domestic cats in Dalian, China.Frontiers in veterinary science · 2022Article
- Molecular characterization ofFrontiers in veterinary science · 2022Article
- Canine parvovirus type 2c in Vietnam continues to produce distinct descendants with new mutations restricted to Vietnamese variants.Archives of virology · 2021Article
- Molecular Epidemiological Survey of Canine Parvovirus Circulating in China from 2014 to 2019.Pathogens (Basel, Switzerland) · 2021Article
- New canine parvovirus 2a infection in an imported Asian small-clawed otter (Aonyx cinereus) in Japan.The Journal of veterinary medical science · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Canine parvovirus type 2 (CPV-2) is an aetiological agent that causes acute haemorrhagic enteritis and fatal myocarditis in dogs. Since CPV-2 first emerged in the late 1970s, its rapid evolution has resulted in three antigenic variants: CPV-2a, CPV-2b and CPV-2c. Here, we report, for the first time in Korea, two cases of CPV-2c infection in two dogs with severe diarrhoea. The complete open reading frame (4,269nt) of CPV-2, encoding both non-structural (NS) and structural (VP) proteins, was sequenced. Based on the amino acid Gln present at residue 426 of the VP2 gene, these strains were typed as CPV-2c, and were named Korea CPV-2c_1 and Korea CPV-2c_2. These strains shared 99.48% reciprocal nucleotide sequence identity and had the highest nucleotide identity (99.77%-99.34%) with Asian CPV strains isolated in China, Italy (found in a dog imported from Thailand), and Vietnam from 2013 to 2017. Phylogenetic analysis based on the non-structural (NS1) and capsid (VP2) genes revealed that Korean CPV-2c strains clustered closely to Asian CPV strains, and separately from strains isolated in Europe, South America and North America. Amino acid changes never reported before were observed in NS1 (Thr70Pro, Cys287Tyr), VP1 (Lys17Arg, Phe33Leu) and VP2 (Gln365His, Ala516Val). Additional observed mutations, including Phe267Tyr, Tyr324Ile and Gln370Arg, have been previously reported in the recent CPV-2c strains with Asian origins. These results suggest that the Korean CPV-2c strains were potentially introduced via neighbouring Asian countries.
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