Evidence map›Paper›PMID 32008580›Full record

ArticlePsychological medicine2021

Posttraumatic stress disorder symptom trajectories within the first year following emergency department admissions: pooled results from the International Consortium to predict PTSD.

Sarah R Lowe, Andrew Ratanatharathorn, Betty S Lai, Willem van der Mei, Anna C Barbano, Richard A Bryant, Douglas L Delahanty, Yutaka J Matsuoka, Miranda Olff, Ulrich Schnyder and 4 more

Open access · greenAbstract read
In one paragraph

Article in Psychological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Post-traumatic stress disorder.Nature reviews. Disease primers · 2026
    Review
  7. Article
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  10. Post-traumatic stress disorder: evolving conceptualization and evidence, and future research directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
    Article
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 5 countries.

Sarah R LoweYale University, School of Public Health.
Andrew RatanatharathornDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York.ORCID 0000-0001-9855-0438
Betty S LaiLynch School of Education and Human Development, Boston College, Chestnut Hill, USA.
Willem van der MeiData Scientist, New York County Defender Services.
Anna C BarbanoDepartment of Psychology, University of Toledo.
Richard A BryantSchool of Psychology, University of New South Wales, Sydney, NSW2052, Australia.
Douglas L DelahantyKent State University, Department of Psychological Sciences, Kent, OH, USA.
Yutaka J MatsuokaDivision of Health Care Research, Center for Public Health Sciences, National Cancer Center Japan, Tokyo, Japan.
Miranda OlffDepartment of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Ulrich SchnyderUniversity of Zurich, Zurich, Switzerland.
Eugene LaskaSteven and Alexandra Cohen Veterans Center for the Study of Posttraumatic Stress and Traumatic Brain Injury, Department of Psychiatry, New York University School of Medicine.
Karestan C KoenenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Arieh Y ShalevDepartment of Psychiatry, New York University School of Medicine, New York, New York.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Harvard University · USNew York University · USArq Psychotrauma Expert Group · NLBoston College · USColumbia University · USDivision of Public Defender Services · USKent State University · USNational Center for Global Health and Medicine · JPThe University of Sydney · AUUniversity of Toledo · USUniversity of Zurich · CHYale University · US

Funding

Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
Identifying Risk Factors for PTSD by Pooled Analysis of Current Prospective StudiR01MH101227 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI KESSLER, RONALD C, KOENEN, KARESTAN C · 2014 to 2017
$2.7M
NIMH NIH HHS R01 MH101227NIMH NIH HHS T32 MH017119
6 · The paper itself

Abstract

backgroundResearch exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics.

methodsThis analysis pooled data from six longitudinal studies of adult survivors of civilian-related injuries admitted to general hospital emergency departments (EDs) in six countries (pooled N = 3083). Each study included at least three assessments of the clinician-administered PTSD scale in the first post-trauma year. Latent class growth analysis determined the proportion of participants exhibiting various PTSD symptom trajectories within and across the datasets. Multinomial logistic regression analyses examined demographic characteristics, type of event leading to the injury, and trauma history as predictors of trajectories differentiated by their initial severity and course.

resultsFive trajectories were found across the datasets: Low (64.5%), Remitting (16.9%), Moderate (6.7%), High (6.5%), and Delayed (5.5%). Female gender, non-white race, prior interpersonal trauma, and assaultive injuries were associated with increased risk for initial PTSD reactions. Female gender and assaultive injuries were associated with risk for membership in the Delayed (v. Low) trajectory, and lower education, prior interpersonal trauma, and assaultive injuries with risk for membership in the High (v. Remitting) trajectory.

conclusionsThe results suggest that over 30% of civilian-related injury survivors admitted to EDs experience moderate-to-high levels of PTSD symptoms within the first post-trauma year, with those reporting assaultive violence at increased risk of both immediate and longer-term symptoms.

Indexed as

AdultEmergency Service, HospitalFemaleHumansLongitudinal StudiesMaleMiddle AgedStress Disorders, Post-TraumaticSurvivorsViolenceLatent class growth analysisposttraumatic stressresiliencetraumatic injuries

Identifiers

PMID32008580
PMCPMC8318129
OpenAlexW3005149671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.