ArticleGenome biology2020
The Deep Genome Project.
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In one paragraph
Article in Genome biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The characteristics of early-stage research into human genes are substantially different from subsequent research.PLoS biology · 2022Pooled it
- The future objectives of the International Mouse Phenotyping Consortium (IMPC): functional evaluation of human disease-relevant cis-regulatory elements in the mouse genome.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- Large-scale mouse mutagenesis identifies novel genes affecting vertebral anatomy.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- Commentary: The International Mouse Phenotyping Consortium: high-throughput in vivo functional annotation of the mammalian genome.Mammalian genome : official journal of the International Mammalian Genome Society · 2024Article
- Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.Scientific reports · 2024Article
- Article
- Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results.bioRxiv : the preprint server for biology · 2024Article
- How much do we know about the function of mammalian genes?BMC biology · 2023Article
- Review
- Genic constraint against nonsynonymous variation across the mouse genome.BMC genomics · 2023Article
- Novel Transcriptomic Interactomes of Noncoding RNAs in the Heart under Altered Thyroid Hormonal States.International journal of molecular sciences · 2023Article
- Mouse tissue glycome atlas 2022 highlights inter-organ variation in major N-glycan profiles.Scientific reports · 2022Article
- Mendelian gene identification through mouse embryo viability screening.Genome medicine · 2022Article
- Phenotype-driven approaches to enhance variant prioritization and diagnosis of rare disease.Human mutation · 2022Review
- Mouse resources at the RIKEN BioResource Research Center and the National BioResource Project core facility in Japan.Mammalian genome : official journal of the International Mammalian Genome Society · 2022Review
- Progress towards completing the mutant mouse null resource.Mammalian genome : official journal of the International Mammalian Genome Society · 2022Article
- Asian Mouse Mutagenesis Resource Association (AMMRA): mouse genetics and laboratory animal resources in the Asia Pacific.Mammalian genome : official journal of the International Mammalian Genome Society · 2022Review
- Mouse mutagenesis and phenotyping to generate models of development and disease.Current topics in developmental biology · 2022Review
- The AKT/mTOR Signaling Pathway Was Mediated through the LINC00514/miR-28-5p/TRIM44 Axis.Disease markers · 2022Article
- Advances in mouse genetics for the study of human disease.Human molecular genetics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
44 authors.
K C Kent LloydDepartment of Surgery, School of Medicine, and Mouse Biology Program, University of California, Davis, CA, 95618, USA. KCLloyd@ucdavis.edu.
David J AdamsWellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
Gareth BaynamWestern Australian Register of Developmental Anomalies and Genetic Services of Western Australia, Department of Health, Government of Western Australia, Perth, Australia.
Arthur L BeaudetDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Fatima BoschCenter of Animal Biotechnology and Gene Therapy, Universitat Autònoma Barcelona, Barcelona, Spain.
Kym M BoycottChildren's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, ON, K1H 8L1, Canada.
Robert E BraunThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Mark CaulfieldGenomics England, William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Ronald CohnThe Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Mary E DickinsonDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Michael S DobbiePhenomics Australia, The Australian National University, 131 Garran Road, Acton, ACT, 2601, Australia.
Ann M FlennikenThe Centre for Phenogenomics, Lunenfeld-Tanenbaum Research Institute, Toronto, ON, M5T 3H7, Canada.
Paul FlicekEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Sanjeev GalandeNational Facility for Gene Function in Health and Disease, Department of Biology, Indian Institute of Science, Education and Research (IISER) Pune, Pune, Maharashtra, 411008, India.
Xiang GaoSKL of Pharmaceutical Biotechnology and Model Animal Research Center, Collaborative Innovation Center for Genetics and Development, Nanjing Biomedical Research Institute, Nanjing University, Nanjing, 210061, China.
Anne GroblerDST/NWU Preclinical Drug Development Platform, North-West University, Potchefstroom, 2520, South Africa.
Jason D HeaneyDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Yann HeraultUniversité de Strasbourg, CNRS, INSERM, Institut de Génétique, Biologie Moléculaire et Cellulaire, Institut Clinique de la Souris, IGBMC, PHENOMIN-ICS, 67404, Illkirch, France.
Martin Hrabě de AngelisGerman Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.
James R LupskiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Stanislas LyonnetInstitut Imagine, UMR-1163 INSERM et Université de Paris, Hôpital Universitaire Necker-Enfants Malades, 24, Boulevard du Montparnasse, 75015, Paris, France.
Ann-Marie MallonMedical Research Council Harwell Institute (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire, OX11 0RD, UK.
Fabio MammanoMonterotondo Mouse Clinic, Italian National Research Council (CNR), Institute of Biochemistry and Cell Biology (IBBC), Monterotondo Scalo, I-00015, Rome, Italy.
Calum A MacRaeDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Roderick McInnesLady Davis Research Institute, Jewish General Hospital, McGill University, 3999 Côte Ste- Catherine Road, Montreal, Quebec, H3T 1E2, Canada.
Colin McKerlieThe Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Terrence F MeehanEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Stephen A MurrayThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Lauryl M J NutterThe Centre for Phenogenomics, The Hospital for Sick Children, Toronto, ON, M5T 3H7, Canada.
Yuichi ObataRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Helen ParkinsonNational Facility for Gene Function in Health and Disease, Department of Biology, Indian Institute of Science, Education and Research (IISER) Pune, Pune, Maharashtra, 411008, India.
Michael S PepperInstitute for Cellular and Molecular Medicine, Department Immunology, and SAMRC Extramural Unit for Stem Cell Research and Therapy, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Radislav SedlacekCzech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, 252 50, Vestec, Czech Republic.
Je Kyung SeongKorea Mouse Phenotyping Consortium (KMPC) and BK21 Program for Veterinary Science, Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, 599 Gwanangno, Gwanak-gu, Seoul, 08826, South Korea.
Toshihiko ShiroishiRIKEN BioResource Research Center, Tsukuba, Ibaraki, 305-0074, Japan.
Damian SmedleyClinical Pharmacology, William Harvey Research Institute, School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.
Glauco Tocchini-ValentiniMonterotondo Mouse Clinic, Italian National Research Council (CNR), Institute of Biochemistry and Cell Biology (IBBC), Monterotondo Scalo, I-00015, Rome, Italy.
David ValleMcKusick-Nathans Department of Genetic Medicine, The Johns Hopkins University School of Medicine, 519 BRB, 733 N Broadway, Baltimore, MD, 21205, USA.
Chi-Kuang Leo WangNational Laboratory Animal Center, National Applied Research Laboratories, Taipei, Taiwan.
Sara WellsMedical Research Council Harwell Institute (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire, OX11 0RD, UK.
Jacqueline WhiteThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Wolfgang WurstInstitute of Developmental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764, Neuherberg, Germany.
Ying XuCambridge-Suda Genomic Resource Center, Jiangsu Key Laboratory of Neuropsychiatric Diseases, Medical College of Soochow University, Suzhou, 215123, Jiangsu, China.
Steve D M BrownMedical Research Council Harwell Institute (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire, OX11 0RD, UK. s.brown@har.mrc.ac.uk.
Funding
UM1HG006348: Cas9 Genome Integrity Supplemental ProposalUM1HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI Jason D. Heaney, Chih-Wei Logan Hsu · 2016 to 2026
$47.5MThe Jackson Laboratory Knockout Mouse Production and Phenotyping Project (JAX KOMP2)UM1OD023222 · OD · JACKSON LABORATORY · PI ROBERT E BRAUN, Stephen A Murray · 2016 to 2026
$47.2MKOMP2-Phase3 Production and Phenotyping by the DTCC Consortium TCP Transfer to UC DavisUM1OD023221 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2016 to 2026
$45.7MMouse Phenotyping Informatics Infrastructure - MP12UM1HG006370 · NHGRI · EUROPEAN MOLECULAR BIOLOGY LABORATORY · PI Pilar Cacheiro Martinez, Helen Elizabeth Parkinson · 2016 to 2026
$20.4MBritish Heart Foundation FS/12/82/29736Medical Research Council G9521010Medical Research Council MC_EX_MR/M009203/1Medical Research Council MC_PC_14089Medical Research Council MC_U142684171Medical Research Council MC_U142684172Medical Research Council MC_UP_1502/1Medical Research Council MR/M009203/1NHGRI NIH HHS UM1 HG006348NHGRI NIH HHS UM1 HG006370NIH HHS UM1 OD023221NIH HHS UM1 OD023222
Abstract
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.