Evidence map›Paper›PMID 32008432›Full record

ReviewHypertension (Dallas, Tex. : 1979)2020

Renal Denervation in Asia: Consensus Statement of the Asia Renal Denervation Consortium.

Kazuomi Kario, Byeong-Keuk Kim, Jiro Aoki, Anthony Yiu-Tung Wong, Ying-Hsiang Lee, Nattawut Wongpraparut, Quang Ngoc Nguyen, Wan Azman Wan Ahmad, Soo Teik Lim, Tiong Kiam Ong and 1 more

Open access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Article
  8. Review
  9. An Update on the Role of Renal Artery Denervation in the Treatment of Hypertension.Current treatment options in cardiovascular medicine · 2025
    Article
  10. Review
  11. Article
  12. What are the ideal metrics for assessing the quality of long-term stabilized "perfect" 24-h BP control after renal denervation?Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. 2023 update and perspectives.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  19. What impacts do the new ESH 2023 guidelines have on the management of hypertension in Japan?Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 11 institutions in 9 countries.

Kazuomi KarioFrom the Department of Cardiovascular Medicine, Jichi Medical University School of Medicine, Tokyo, Japan (K.K.).
Byeong-Keuk KimDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea (B.-K.K.).
Jiro AokiDivision of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (J.A.).
Anthony Yiu-Tung WongDivision of Cardiology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, HKSAR (A.Y.-T.W.).
Ying-Hsiang LeeCardiovascular Center, MacKay Memorial Hospital, Taipei, Taiwan (Y.-H.L.).
Nattawut WongpraparutDivision of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand (N.W.).
Quang Ngoc NguyenDepartment of Cardiology, Hanoi Medical University, Vietnam (Q.N.N.).
Wan Azman Wan AhmadDivision of Cardiology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia (W.A.W.A).
Soo Teik LimDepartment of Cardiology, National Heart Center, Singapore (S.T.L.).
Tiong Kiam OngDepartment of Cardiology, Sarawak Heart Centre, Malaysia (T.K.O.).
Tzung-Dau WangCardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (T.-D.W.).
Hanoi Medical University · VNJichi Medical University · JPMackay Medical University · TWMahidol University · THMitsui Memorial Hospital · JPNational Heart Centre Singapore · SGNational Taiwan University Hospital · TWSarawak Biodiversity Centre · MYSeverance Hospital · KRUniversity of Hong Kong · HKUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Asia Renal Denervation Consortium consensus conference of Asian physicians actively performing renal denervation (RDN) was recently convened to share up-to-date information and regional perspectives, with the goal of consensus on RDN in Asia. First- and second-generation trials of RDN have demonstrated the efficacy and safety of this treatment modality for lowering blood pressure in patients with resistant hypertension. Considering the ethnic differences of the hypertension profile and demographics of cardiovascular disease demonstrated in the SYMPLICITY HTN (Renal Denervation in Patients With Uncontrolled Hypertension)-Japan study and Global SYMPLICITY registry data from Korea and Taiwan, RDN might be an effective hypertension management strategy in Asia. Patient preference for device-based therapy should be considered as part of a shared patient-physician decision process. A practical population for RDN treatment could consist of Asian patients with uncontrolled essential hypertension, including resistant hypertension. Opportunities to refine the procedure, expand the therapy to other sympathetically mediated diseases, and explore the specific effects on nocturnal and morning hypertension offer a promising future for RDN. Based on available evidence, RDN should not be considered a therapy of last resort but as an initial therapy option that may be applied alone or as a complementary therapy to antihypertensive medication.

Indexed as

Blood PressureConsensusDenervationHumansHypertensionKidneyTreatment OutcomeAsiablood pressurecardiovascular diseasesdenervationpopulation

Identifiers

PMID32008432
PMCPMC8032219
OpenAlexW3006004269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.