Evidence map›Paper›PMID 32008168›Full record

ArticleEuropean child & adolescent psychiatry2020

Co-occurring obsessive-compulsive disorder and autism spectrum disorder in young people: prevalence, clinical characteristics and outcomes.

Alex F Martin, Amita Jassi, Alexis E Cullen, Matthew Broadbent, Johnny Downs, Georgina Krebs

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European child & adolescent psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alex F MartinDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London, SE5 8AF, UK. alex.martin@kcl.ac.uk.ORCID http://orcid.org/0000-0003-1097-1137
Amita JassiOCD, BDD and Related Disorders Clinic, South London and Maudsley NHS Trust, London, UK.ORCID http://orcid.org/0000-0003-1006-3008
Alexis E CullenDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-3178-3920
Matthew BroadbentNIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation, London, UK.
Johnny DownsNIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation, London, UK.ORCID http://orcid.org/0000-0002-8061-295X
Georgina KrebsOCD, BDD and Related Disorders Clinic, South London and Maudsley NHS Trust, London, UK.ORCID http://orcid.org/0000-0002-5353-5645
King's College London · GBSouth London and Maudsley NHS Foundation Trust · GB

Funding

Department of Health CS-2018-18-ST2-014Economic and Social Research Council ES/J500057/1Medical Research Council MR/L017105/1Medical Research Council MR/N001400/1Wellcome TrustWellcome Trust 107395/Z/15/Z
6 · The paper itself

Abstract

Obsessive-compulsive disorder (OCD) and autism spectrum disorders (ASD) commonly co-occur and are considered challenging to manage when they co-occur in youth. However, clinical characteristics and prognosis of this group remain poorly understood. This study examined the prevalence, clinical correlates and outcomes of paediatric OCD co-occurring with ASD (OCD + ASD) in a large clinical cohort. Data were extracted from electronic clinical records of young people aged 4-17 years who had attended a mental health trust in South London, United Kingdom. We identified young people with diagnoses of OCD + ASD (n = 335), OCD without ASD (n = 1010), and ASD without OCD (n = 6577). 25% of youth with OCD had a diagnosis of ASD, while 5% of those with ASD had a diagnosis of OCD. At diagnosis, youth with OCD + ASD had lower psychosocial functioning scores on the clinician-rated Child Global Assessment Scale (CGAS) compared to those with either OCD or ASD. Youth with OCD + ASD were equally likely to receive CBT compared to those with OCD but were more likely to be prescribed medication and use services for longer than either comparison group. Youth with OCD + ASD showed significant improvements in functioning (CGAS scores) after service utilisation but their gains were smaller than those with OCD. OCD + ASD commonly co-occur, conferring substantial impairment, although OCD may be underdiagnosed in youth with ASD. Young people with co-occurring OCD + ASD can make significant improvements in functioning with routine clinical care but are likely to remain more impaired than typically developing youth with OCD, indicating a need for longer-term support for these young people.

Indexed as

AdolescentAutism Spectrum DisorderChildChild, PreschoolComorbidityFemaleHumansMaleObsessive-Compulsive DisorderPrevalencePrognosisTreatment OutcomeAutism spectrum disordersComorbidityObsessive–compulsive disorderPsychosocial functioningTreatment outcomes

Identifiers

PMID32008168
PMCPMC7595977
OpenAlexW3003332956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.