ReviewDigestive diseases and sciences2020
Necrotizing Enterocolitis: A Multi-omic Approach and the Role of the Microbiome.
Review in Digestive diseases and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Evolving role of mitochondrial dysfunction and mitophagy in necrotizing enterocolitis.Pediatric research · 2026Article
- The microbiome's hidden influence: preclinical insights into inflammatory responses in necrotizing enterocolitis.Seminars in immunopathology · 2025Review
- Article
- The conundrum of intestinal injury in preterm infants receiving mother's own milk.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- Chromatin as alarmins in necrotizing enterocolitis.Frontiers in immunology · 2024Review
- Neonatal Microbiome: Is it Still Beneficial?Endocrine, metabolic & immune disorders drug targets · 2024Article
- New insights into the pathogenesis of necrotizing enterocolitis and the dawn of potential therapeutics.Seminars in pediatric surgery · 2023Review
- Probiotic-educated Tregs are more potent than naïve Tregs for immune tolerance in stressed new-born mice.Beneficial microbes · 2023Article
- Multiomics, artificial intelligence, and precision medicine in perinatology.Pediatric research · 2023Review
- Bench to bedside - new insights into the pathogenesis of necrotizing enterocolitis.Nature reviews. Gastroenterology & hepatology · 2022Review
- A new intestinal ultrasound integrated approach for the management of neonatal gut injury.European journal of pediatrics · 2022Review
- Review
- Influence of Human Milk on Very Preterms' Gut Microbiota and Alkaline Phosphatase Activity.Nutrients · 2021Observational
- Dynamics of the preterm gut microbiome in health and disease.American journal of physiology. Gastrointestinal and liver physiology · 2021Review
- The protective effect and mechanism of epidermal growth factor on necrotizing enterocolitis in a neonatal rat model.Translational pediatrics · 2021Article
- Necrotizing Enterocolitis in Neonates With Hyperinsulinemic Hypoglycemia Treated With Diazoxide.Pediatrics · 2021Article
- Preterm Delivery: Microbial Dysbiosis, Gut Inflammation and Hyperpermeability.Frontiers in microbiology · 2021Article
- T Lymphocytes, Multi-Omic Interactions and Bronchopulmonary Dysplasia.Frontiers in pediatrics · 2021Review
- Probiotics, Prebiotics, and Synbiotics for the Prevention of Necrotizing Enterocolitis.Frontiers in nutrition · 2021Review
- Intestinal Dysbiosis As a Possible Predictor of Very Early Preterm Labor in Pregnant Women With Metabolic Syndrome.Journal of medicine and lifeArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Necrotizing enterocolitis (NEC) is a poorly defined disease that primarily affects preterm infants. There has not been much progress in the prevention or treatment of NEC since it became recognized as a common problem in preterm infants. Reasons for this lack of progress include the likelihood that different diseases are being put under the same moniker of "NEC," similar to using "diabetes" for the different diseases it represents. In order to make progress, better delineation of the phenotypes that present as NEC will be necessary to clearly establish their pathophysiology, find specific and sensitive biomarkers, and establish preventative regimens. In this review, we summarize some of the entities that are being called NEC, discuss the pathophysiology of the most classic form of NEC, and provide an overview of how we might proceed in the future to make progress in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.