Evidence map›Paper›PMID 32008126›Full record

ArticleChild psychiatry and human development2020

Psychiatric Disorders in the Adolescent Offspring of Mothers with Thyroid Problems During Pregnancy.

Jacob Young, Calan Savoy, Ian Colman, Mark Ferro, Ryan J Van Lieshout

Abstract read
PubMed Publisher
In one paragraph

Article in Child psychiatry and human development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Perinatal Factors and Emotional, Cognitive, and Behavioral Dysregulation in Childhood and Adolescence.Journal of the American Academy of Child and Adolescent Psychiatry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jacob YoungDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada. youngjm@mcmaster.ca.ORCID 0000-0002-4206-8076
Calan SavoyDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Ian ColmanSchool of Epidemiology, Public Health, and Preventive Medicine, University of Ottawa, Ottawa, ON, Canada.
Mark FerroSchool of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada.
Ryan J Van LieshoutDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
McMaster University · CAUniversity of Ottawa · CAUniversity of Waterloo · CA

Funding

CIHR 125941CIHR FRN111110
6 · The paper itself

Abstract

Maternal thyroid problems during pregnancy have been linked to neurocognitive impairments in children. While studies suggest that disorders of maternal thyroid function during pregnancy are associated with symptoms of mental health problems in children, little is known about the risk of clinically significant psychiatric disorders in adolescence. A sample of 2451 Canadian adolescents enrolled in the Ontario Child Health Study completed the Mini International Neuropsychiatric Interview for Children and Adolescents at 12-17 years of age. Their mothers self-reported thyroid problems during pregnancy. Gestational thyroid problems were associated with offspring oppositional defiant disorder (ODD; OR 3.73; 95% CI 1.69-8.24), conduct disorder (CD; OR 12.95; 95% CI 5.12-32.75), and social anxiety disorder (SAD; OR 6.25; 95% CI 2.53-15.47). Neither sex nor gestational age moderated associations between prenatal thyroid dysfunction and the majority of outcomes. School performance mediated 8% of the association between thyroid problems and SAD, 21% for CD and 53% for ODD.

Indexed as

Academic PerformanceAdolescentAttention Deficit and Disruptive Behavior DisordersChildConduct DisorderFemaleHumansMaleOntarioPhobia, SocialPregnancyPrenatal Exposure Delayed EffectsThyroid DiseasesAdolescenceGestationMental disordersPregnancyThyroid diseases

Identifiers

PMID32008126
OpenAlexW3003661931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.