Evidence map›Paper›PMID 32007643›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak.

Shi Zhao, Qianyin Lin, Jinjun Ran, Salihu S Musa, Guangpu Yang, Weiming Wang, Yijun Lou, Daozhou Gao, Lin Yang, Daihai He and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04328493 (A Multi Center Randomized Open Label Trial on the Safety and Efficacy of Chloroquine for the Treatment of Hospitalized Adults With Laboratory Confirmed SARS-CoV-2 Infection in Vietnam), which is not on this map. Cited by 755 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
755citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04328493 phase2completednot on this map

A Multi Center Randomized Open Label Trial on the Safety and Efficacy of Chloroquine for the Treatment of Hospitalized Adults With Laboratory Confirmed SARS-CoV-2 Infection in Vietnam

TypeinterventionalSponsorOxford University Clinical Research Unit, VietnamRan2020 to 2020Enrolled10ConditionsSARS-CoV-2 Infection, COVID-19ArmsChloroquine phosphate
3 · Its place in the literature

Who cites it

755 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  19. Pathogenic mechanisms of cardiovascular damage in COVID-19.Molecular medicine (Cambridge, Mass.) · 2024
    Review
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695 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Shi ZhaoJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; Shenzhen Research Institute of Chinese University of Hong Kong, Shenzhen, China. Electronic address: shi.zhao@link.cuhk.edu.hk.
Qianyin LinMichigan Institute for Data Science, University of Michigan, Ann Arbor, MI, USA. Electronic address: qianying.lin@connect.polyu.hk.
Jinjun RanSchool of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China. Electronic address: jimran@connect.hku.hk.
Salihu S MusaDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China. Electronic address: salihu-sabiu.musa@connect.polyu.hk.
Guangpu YangDepartment of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong, China; SH Ho Scoliosis Research Lab, Joint Scoliosis Research Center of Chinese University of Hong Kong and Nanjing University, Hong Kong, China. Electronic address: kennethgpy@link.cuhk.edu.hk.
Weiming WangSchool of Mathematics and Statistics, Huaiyin Normal University, Huaian, China. Electronic address: weimingwang2003@163.com.
Yijun LouDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China. Electronic address: yijun.lou@polyu.edu.hk.
Daozhou GaoDepartment of Mathematics, Shanghai Normal University, Shanghai, China. Electronic address: dzgao@shnu.edu.cn.
Lin YangSchool of Nursing, Hong Kong Polytechnic University, Hong Kong, China. Electronic address: l.yang@polyu.edu.hk.
Daihai HeDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China. Electronic address: daihai.he@polyu.edu.hk.
Maggie H WangJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China; Shenzhen Research Institute of Chinese University of Hong Kong, Shenzhen, China. Electronic address: maggiew@cuhk.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsAn ongoing outbreak of a novel coronavirus (2019-nCoV) pneumonia hit a major city in China, Wuhan, December 2019 and subsequently reached other provinces/regions of China and other countries. We present estimates of the basic reproduction number, R

methodsAccounting for the impact of the variations in disease reporting rate, we modelled the epidemic curve of 2019-nCoV cases time series, in mainland China from January 10 to January 24, 2020, through the exponential growth. With the estimated intrinsic growth rate (γ), we estimated R

findingsThe early outbreak data largely follows the exponential growth. We estimated that the mean R

conclusionThe mean estimate of R

Indexed as

Basic Reproduction NumberBetacoronavirusChinaCoronavirus InfectionsCOVID-19EpidemicsHumansMiddle East Respiratory Syndrome CoronavirusPandemicsPneumonia, ViralSARS-CoV-2Severe acute respiratory syndrome-related coronavirusWorld Health OrganizationBasic reproduction numberNovel coronavirus (2019-nCoV)

Identifiers

PMID32007643
PMCPMC7110798

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.