ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2020
Atypical Cortical Activation During Risky Decision Making in Disruptive Behavior Disordered Youths With Histories of Suicidal Ideation.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- A Systematic Review of MRI Studies and the "Emotional paiN and social Disconnect (END)" Brain Model of Suicidal Behavior in Youth.Behavioural neurology · 2023Pooled it
- Adaptations of the balloon analog risk task for neuroimaging settings: a systematic review.Frontiers in neuroscience · 2023Pooled it
- Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients.eLife · 2026Article
- Familial risk factors required to predict earlier adolescent substance use in youth with externalizing disorders.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Introducing the Glutamate-Amplifies-Noradrenergic-Effects (GANE) Model to the Neurocognitive Study of Emotion-Related Impulsivity.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Sex differences in Cingulo-Opercular activation during risky decision-making in youth with externalizing disorders.Psychiatry research. Neuroimaging · 2025Article
- Neural correlates of decision making and executive function in suicidal thoughts and behaviors.Frontiers in psychiatry · 2025Review
- Sex differences in reward network activation are linked to problematic substance use among high-risk adolescents.Advances in drug and alcohol research · 2025Article
- Profiles of HIV-Related Knowledge and Self-Regulation Factors in At-Risk Pre-Adolescents.Children's health care : journal of the Association for the Care of Children's Health · 2025Article
- Family history of substance use disorder and parental impulsivity are differentially associated with neural responses during risky decision-making.Frontiers in neuroimaging · 2023Article
- Abnormal brain activity in nonsuicidal self-injury: a coordinate-based activation likelihood meta-analysis of functional neuroimaging studies.Psychoradiology · 2021Article
- Multimodal Elements of Suicidality Reduction After Transcranial Magnetic Stimulation.Neuromodulation : journal of the International Neuromodulation Society · 2021Article
- Translating Interventional Neuroscience to Suicide: It's About Time.Biological psychiatry · 2021Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSuicidality is a leading cause of death among adolescents. In addition to other psychiatric conditions, youths with attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior disorders (DBDs) are at heightened risk for suicide. Decision-making deficits are a hallmark symptom of ADHD and DBDs and are also implicated in suicidal behavior. We examined behavioral and neural differences in decision making among youths with ADHD and DBDs with (SI+) and without (SI-) histories of suicidal ideation.
methodsThe Balloon Analog Risk Task, a risky decision-making task, was completed by 57 youths with ADHD and DBDs (38% SI+) during functional magnetic resonance imaging. Mean stop wager (mean wager at which youths bank money) was the primary measure of risk taking. We conducted whole-brain and region-of-interest analyses in the anterior cingulate cortex and orbitofrontal cortex (OFC) during choice (win vs. inflate) and outcome (inflate vs. explode) contrasts using parametric modulators accounting for probability of balloon explosion.
resultsThere were no differences between SI+ and SI- youths in Balloon Analog Risk Task performance. SI+ youths showed decreasing activation in the right medial frontal gyrus when choosing inflate as explosion probability increased compared with SI- youths. During explosions, SI- youths showed increasing activation in the left OFC as explosions became more likely. SI+ showed increasing left medial OFC activity in response to inflations as explosion probability increased.
conclusionsSI+ youths may show heightened sensitivity to immediate reward and decreased sensitivity to potential loss as evidenced by medial frontal gyrus activity. OFC findings suggest that SI+ youths may be drawn to reward even when there is high probability of loss.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.