ArticleJournal of neuro-oncology2020
Transcortical approach for insular gliomas: a series of 253 patients.
Article in Journal of neuro-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Transcortical versus transsylvian approaches for adult insular glioma resection: a systematic review with subanalysis by Berger-Sanai segmentation.Neurosurgical review · 2026Pooled it
- Transcortical versus Transsylvian Approach for Insular Gliomas: A Systematic Review and Meta-Analysis.Asian journal of neurosurgery · 2026Review
- Surgical timing guided by progressive cognitive decline in a left insular tumor without neurological deficits: A case report.Surgical neurology international · 2026Article
- The specific linear or curved boundaries between WHO grade II-III insular gliomas and the basal ganglia indicate distinct biological features, survival outcomes, and surgical strategies: evidence from 330 cases.NeuroImage. Clinical · 2026Article
- Predicting Extent of Resection and Neurological Outcome for Insular Gliomas: An Analysis of Two Available Classifications.Cancers · 2024Article
- Frontal trans opercular approaches to the insula: building the mental picture from procedure-guided anatomical dissection.Surgical and radiologic anatomy : SRA · 2024Article
- Survival outcome and predictors of WHO grade 2 and 3 insular gliomas: A classification based on the tumor spread.Cancer medicine · 2024Article
- Factors affecting the extent of resection and neurological outcomes following transopercular resection of insular gliomas.Acta neurochirurgica · 2024Article
- Cortical incisions and transcortical approaches for intra-axial and intraventricular lesions: A scoping review.Surgical neurology international · 2024Article
- Prognostic Factors and Resectability Predictors in Insular Gliomas: A Systematic Review.Journal of neurological surgery. Part A, Central European neurosurgery · 2024Article
- What is the cognitive footprint of insular glioma?Frontiers in human neuroscience · 2024Review
- Surgical treatment for insular gliomas. A systematic review and meta-analysis on behalf of the EANS neuro-oncology section.Brain & spine · 2024Review
- Anatomical aspects of the insula, opercula and peri-insular white matter for a transcortical approach to insular glioma resection.Neurosurgical review · 2022Article
- Incidence of ischemic complications and technical nuances of arteries preservation for insular gliomas resection.Frontiers in surgery · 2022Article
- Contralesional Structural Plasticity in Different Molecular Pathologic Subtypes of Insular Glioma.Frontiers in neurology · 2021Article
- Awake Surgery for Left Posterior Insular Low-Grade Glioma Through the Parietorolandic Operculum: The Need to Preserve the Functional Connectivity. A Case Series.Frontiers in surgery · 2021Article
- Challenging Giant Insular Gliomas With Brain Mapping: Evaluation of Neurosurgical, Neurological, Neuropsychological, and Quality of Life Results in a Large Mono-Institutional Series.Frontiers in oncology · 2021Article
- Prediction of Lower Grade Insular Glioma Molecular Pathology Using Diffusion Tensor Imaging Metric-Based Histogram Parameters.Frontiers in oncology · 2021Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe object of this study was to identify the distribution characteristics of insular gliomas and evaluate the efficiency of transcortical approach.
methodsInsular gliomas patients who underwent transcortical approach for the first time between March 2011 and July 2019 at our institute were analyzed.
resultsA total of 253 primary insular gliomas patients were enrolled in the study. Of all patients, 176 patients (69.6%) underwent gross total resection, 61 patients (24.1%) underwent subtotal resection and 16 patients (6.3%) underwent partial resection. According to Berger-Sanai classification, the gross total resection rates of different types of insular gliomas were as follows: Zone I (90.1%), zone II (50.0%), zone III (40.0%), zone IV (89.5%), zone I + II (43.5%), zone I + IV (74.6%), zone II + III (44.4%), zone III + IV (41.7%), Giant (34.5%). According to our modified classification, the gross total resection rates were as follows: anterior type (84.9%), posterior type (45.8%), anterior-posterior type (42.9%), giant type (34.5%). After surgery, new limb motor deficit was observed in 28 patients (11.1%), and 5 patients (2.0%) were left long-term limb motor disability. New language impairment occurred in 23 patients (9.1%), and 3 patients (1.2%) were left long-term language disability. The patients were followed up for 1 to 89.2 months (average, 39.9 ± 20.3 months). At the end of follow-up, tumor progression occurred in 98 (38.7%) patients and 71 (28.1%) patients died of their disease.
conclusionThis study demonstrated that the maximal safe resection of insular gliomas can be achieved by transcortical approach. Insular gliomas had the characteristic of forward distribution, anterior transcortical approach can provide enough surgical freedom for anterior type of insular gliomas. If anterior tumors can make route to the posterior parts, anterior transcortical approach was also applied to some anterior-posterior and giant types of insular gliomas without resection of excessive brain, which may reduce the incidence of neurological complications.
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