Evidence map›Paper›PMID 32006147›Full record

ReviewBrain structure & function2020

Investigating learning-related neural circuitry with chronic in vivo optical imaging.

Christian R Lee, Laleh Najafizadeh, David J Margolis

Abstract readReview
In one paragraph

Review in Brain structure & function, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christian R LeeDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.
Laleh NajafizadehDepartment of Electrical and Computer Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.
David J MargolisDepartment of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA. david.margolis@rutgers.edu.ORCID http://orcid.org/0000-0002-2678-4216

Funding

Neural circuit mechanisms underlying cognitive control of sensory-guided behaviorR01NS094450 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI David J Margolis · 2016 to 2026
$3.6M
National Science Foundation CBET-1605646National Science Foundation IOS-1845355New Jersey Commission on Brain Injury Research CBIR16IRG032NIH HHS R01NS094450NINDS NIH HHS R01 NS094450
6 · The paper itself

Abstract

Fundamental aspects of brain function, including development, plasticity, learning, and memory, can take place over time scales of days to years. Chronic in vivo imaging of neural activity with cellular resolution is a powerful method for tracking the long-term activity of neural circuits. We review recent advances in our understanding of neural circuit function from diverse brain regions that have been enabled by chronic in vivo cellular imaging. Insight into the neural basis of learning and decision-making, in particular, benefit from the ability to acquire longitudinal data from genetically identified neuronal populations, deep brain areas, and subcellular structures. We propose that combining chronic imaging with further experimental and computational innovations will advance our understanding of the neural circuit mechanisms of brain function.

Indexed as

Neuronal PlasticityOptical ImagingAnimalsBehavior, AnimalBrainDecision MakingElectrodes, ImplantedHumansLearningNeural PathwaysNeuronsComputationGECIsImagingLearningNeural circuitsPlasticitySensory processing

Identifiers

PMID32006147
PMCPMC8663021

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.