ArticleRice (New York, N.Y.)2020
MINI SEED 2 (MIS2) Encodes a Receptor-like Kinase that Controls Grain Size and Shape in Rice.
Article in Rice (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed.
- Enhancing drought stress tolerance of NIL-SUB1DRO1 rice strain through different seed priming treatments.Scientific reports · 2026Article
- Wheat Plasma Membrane Receptors: Orchestrating Immunity and Bridging to Crop Improvement.Current issues in molecular biology · 2025Review
- Overexpression of TaCR4-A positively regulates grain size in Triticum aestivum.BMC plant biology · 2025Article
- Genome wide association studies on seven yield-related traits of 183 rice varieties in Bangladesh.Plant direct · 2024Article
- OsCRLK2, a Receptor-Like Kinase Identified by QTL Analysis, is Involved in the Regulation of Rice Quality.Rice (New York, N.Y.) · 2024Article
- Beyond skin-deep: targeting the plant surface for crop improvement.Journal of experimental botany · 2023Review
- Molecular characterization reveals that OsSAPK3 improves drought tolerance and grain yield in rice.BMC plant biology · 2023Article
- Positional cloning identified HvTUBULIN8 as the candidate gene for round lateral spikelet (RLS) in barley (Hordeum vulgare L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- A putative SUBTILISIN-LIKE SERINE PROTEASE 1 (SUBSrP1) regulates anther cuticle biosynthesis and panicle development in rice.Journal of advanced research · 2022Article
- Developing Genetic Engineering Techniques for Control of Seed Size and Yield.International journal of molecular sciences · 2022Review
- ERECTA regulates seed size independently of its intracellular domain via MAPK-DA1-UBP15 signaling.The Plant cell · 2022Article
- Reference genome assemblies reveal the origin and evolution of allohexaploid oat.Nature genetics · 2022Article
- Exploration of the genomic atlas of Dof transcription factor family across genusFrontiers in plant science · 2022Article
- Identification and Comprehensive Genome-Wide Analysis of Glutathione S-Transferase Gene Family in Sweet Cherry (Frontiers in plant science · 2022Article
- Comparative transcriptome analysis, unfolding the pathways regulating the seed-size trait in cultivated lentil (Frontiers in genetics · 2022Article
- Unveiling the genetic architecture for lodging resistance in rice (Frontiers in genetics · 2022Article
- Comprehensive Comparative Analysis of the GATA Transcription Factors in Four Rosaceae Species and Phytohormonal Response in Chinese Pear (International journal of molecular sciences · 2021Article
- Thermal Stresses in Maize: Effects and Management Strategies.Plants (Basel, Switzerland) · 2021Review
- Comprehensive Transcriptome Analyses Reveal Candidate Genes for Variation in Seed Size/Weight During Peanut (Frontiers in plant science · 2021Article
- Discovery of genomic regions and candidate genes for grain weight employing next generation sequencing based QTL-seq approach in rice (Oryza sativa L.).Molecular biology reports · 2020Article
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7 authors.
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Abstract
backgroundGrain size is a key agronomic trait that is directly associated with grain yield in rice. Although several genes related to grain size in rice have been identified, our understanding of the mechanism of grain development is still limited.
resultsIn this study, we reported the characterization of a novel seed size mutant mini seed 2 (mis2), in which the grain showed reduced length, width and thickness along with wrinkled surface. Microscopic analysis revealed that the spikelet epidermal cell size was reduced but the cell number was increased in the mis2 mutant, suggesting that MIS2 controls grain size by coordinately regulating epidermal cell size and cell number. Map-based cloning revealed that MIS2 encodes a receptor-like kinase CRINKLY4 (CR4) which showed the highest expression in developing panicles. The MIS2 protein is localized primarily on the plasma membrane along with the endosome. However, the Arg258Gln mutation located in extracellular domain in the mis2 mutant disturbed its subcellular localization. Additionally, three major haplotypes of MIS2 were identified in the japonica, indica and aus rice cultivars. The 18-bp InDel (insertion and deletion) in the 5'-UTR (untranslated region) caused different expression level of MIS2 in haplotypes.
conclusionsWe reported a key role of OsCR4 in controlling grain size and shape by coordinately regulating epidermal cell size and cell number. The Arg258 in the extracellular seven-repeat domain is essential for the correct subcellular behavior and function of the OsCR4 protein.
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