Evidence map›Paper›PMID 32005982›Full record

ArticleNature protocols2020

Isolation of tissue-resident vascular endothelial stem cells from mouse liver.

Hisamichi Naito, Taku Wakabayashi, Masako Ishida, Chang-Hyun Gil, Tomohiro Iba, Fitriana Nur Rahmawati, Shota Shimizu, Mervin C Yoder, Nobuyuki Takakura

Abstract read
PubMed Publisher
In one paragraph

Article in Nature protocols, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. CD157Stem cell reports · 2026
    Article
  2. Review
  3. CD157Inflammation and regeneration · 2025
    Article
  4. Review
  5. Metformin synergizes with PD-1 blockade to promote normalization of tumor vessels via CD8T cells and IFNγ.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Bone marrow stromal cell antigen-1 deficiency protects from acute kidney injury.American journal of physiology. Renal physiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. NADCell & bioscience · 2023
    Review
  12. Review
  13. NADOxidative medicine and cellular longevity · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Hisamichi NaitoDepartment of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan. naitohi@biken.osaka-u.ac.jp.ORCID http://orcid.org/0000-0002-0750-1743
Taku WakabayashiDepartment of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Masako IshidaDepartment of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Chang-Hyun GilIndiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA.
Tomohiro IbaDepartment of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Fitriana Nur RahmawatiDepartment of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Shota ShimizuDepartment of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Mervin C YoderIndiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, USA. myoder@iu.edu.ORCID http://orcid.org/0000-0003-4354-7631
Nobuyuki TakakuraDepartment of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan. ntakaku@biken.osaka-u.ac.jp.ORCID http://orcid.org/0000-0003-0397-8605
The University of Osaka · JPIndiana University School of MedicineOsaka International University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial cells (ECs) are fundamental components of the blood vessels that comprise the vascular system; facilitate blood flow; and regulate permeability, angiogenesis, inflammatory responses and homeostatic tissue maintenance. Accumulating evidence suggests there is EC heterogeneity in vivo. However, isolation of fresh ECs from adult mice to investigate this further is challenging. Here, we describe an easy and reproducible protocol for isolation of different types of ECs and CD157

Indexed as

AnimalsCytological TechniquesEndothelial CellsLiverMiceStem Cells

Identifiers

PMID32005982
OpenAlexW3003809815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.