ArticleScientific reports2020
Association between diabetes and cognitive function at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA- Brasil).
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 62 citations in OpenAlex.
- Applications of Continuous Glucose Monitoring in Cognitive Research in Diabetes: a Scoping Review.Current diabetes reports · 2026Article
- Diabetes and cognitive health in India: a nationally representative survey of adults aged 45 years and older.BMJ open · 2025Article
- Translational disease modeling of peripheral blood identifies type 2 diabetes biomarkers predictive of Alzheimer's disease.NPJ systems biology and applications · 2025Article
- Cognitive dysfunction in diabetes-related foot complications: A cohort study.Journal of diabetes and metabolic disorders · 2024Article
- Article
- Type II diabetes and cognitive function among older adults in India and China-results from Harmonized Cognitive Assessment Protocol studies.Frontiers in public health · 2024Article
- Analysis of current situation and influencing factors of cognitive dysfunction associated with type 2 diabetes and follow-up study on treatment effectiveness.Frontiers in neurology · 2024Article
- Risk Factors for Various Cognitive Function Decline Trajectories in Adults Over 40 Years of Age: A Retrospective Cohort Study.Psychiatry investigation · 2023Article
- Molecular and neural roles of sodium-glucose cotransporter 2 inhibitors in alleviating neurocognitive impairment in diabetic mice.Psychopharmacology · 2023Article
- Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists.Theranostics · 2023Review
- Variations in cognition by human capital characteristics: a cross-sectional analysis of Brazilian older adults.Frontiers in public health · 2023Article
- Cognition and BDNF levels in prediabetes and diabetes: A mediation analysis of a cross-sectional study.Frontiers in endocrinology · 2023Article
- Association between cognitive capacity and metabolic indices in patients with neuropsychiatric disorders.Journal of education and health promotion · 2023Article
- Amyloid Fibrillation of Insulin: Amelioration Strategies and Implications for Translation.ACS pharmacology & translational science · 2022Review
- Differences in the Association of Select Dietary Measures With Risk of Incident Type 2 Diabetes.Diabetes care · 2022Article
- Association between Sedentary Behavior and Cognitive Performance in Middle-Aged and Elderly Adults: Cross-Sectional Results from ELSA-Brasil.International journal of environmental research and public health · 2022Article
- Diagnosis of vascular cognitive impairment: recommendations of the scientific department of cognitive neurology and aging of the Brazilian Academy of Neurology.Dementia & neuropsychologia · 2022Article
- Neurocognitive screening in patients following SARS-CoV-2 infection: tools for triage.BMC neurology · 2022Article
- Preventable risk factors of dementia: Population attributable fractions in a Brazilian population-based study.Lancet regional health. Americas · 2022Article
- Neurocognitive Screening in Patients Following SARS-CoV-2 Infection: Tools for Triage.Research square · 2022Article
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes has been associated with cognitive changes and an increased risk of vascular dementia and Alzheimer's disease, but it is unclear whether there are associations between diabetes and early alterations in cognitive performance. The present study consisted of a cross-section analysis of 14,444 participants aged 35-74 years and from a developing country at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil); these participants were recruited between 2008 and 2010. We investigated whether there was an association between diabetes and early changes in the cognitive performance of this Brazilian population. To assess cognitive domains, we used the word-list learning, word-list delayed recall and word recognition tests along. Phonemic verbal fluency tests included semantic phonemic test (animals) and a phonemic test (words beginning with the letter F). Executive functions associated with attention, concentration and psychomotor speed were evaluated using the Trail Making Test B. The exposure variable in the study was defined as diabetes. Multiple linear regression was used to estimate the association between diabetes and cognitive performance. The results were adjusted for age, sex, education, hypertension, coronary disease, depression, physical activity, smoking, alcohol consumption, and the cholesterol/HDL-C ratio. We found a significant association between diabetes and decreased memory, language and executive function (attention, concentration and psychomotor speed) performance in this population from a country with a distinct epidemiological profile, even after adjusting for the main intervening variables.
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