Evidence map›Paper›PMID 32005680›Full record

ArticleScience immunology2020

Technical comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

A J Salinger, M L Dubuke, C Carmona-Rivera, A J Maurais, S A Shaffer, E Weerapana, P R Thompson, M J Kaplan

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Science immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Protein citrullination: inhibition, identification and insertion.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

A J SalingerDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
M L DubukeDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.ORCID 0000-0002-7605-9098
C Carmona-RiveraSystemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-7706-1464
A J Maurais
S A ShafferDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.ORCID 0000-0002-5264-3257
E WeerapanaDepartment of Chemistry, Boston College, Chestnut Hill, MA 02467, USA.
P R ThompsonDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Paul.Thompson@umassmed.edu mariana.kaplan@nih.gov.ORCID 0000-0002-1621-3372
M J KaplanSystemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Paul.Thompson@umassmed.edu mariana.kaplan@nih.gov.ORCID 0000-0003-2968-0815

Funding

Systemic AutoimmunityZIAAR041199 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KAPLAN, MARIANA · 2014 to 2025
$32.5M
Chemical probes to decipher PAD biologyR35GM118112 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Paul R Thompson · 2016 to 2026
$9.5M
Investigating cysteine-mediated protein activities in C. elegansR01GM118431 · NIGMS · BOSTON COLLEGE · PI WEERAPANA, ERANTHIE · 2015 to 2019
$1.8M
Investigating cysteine PTMs in living cellsR01GM117004 · NIGMS · BOSTON COLLEGE · PI WEERAPANA, ERANTHIE · 2016 to 2019
$1.2M
Exploration of the cellular citrullome using novel mass spectrometry toolsF32GM128231 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SALINGER, ARI · 2018 to 2020
$132k
Intramural NIH HHS ZIA AR041199NIGMS NIH HHS F32 GM128231NIGMS NIH HHS R01 GM117004NIGMS NIH HHS R01 GM118431NIGMS NIH HHS R35 GM118112
6 · The paper itself

Abstract

Reassessment of citrullinome cargo in neutrophil extracellular traps confirms the presence of citrullinated peptides.

Identifiers

PMID32005680
PMCPMC7043321

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.