ArticleOccupational and environmental medicine2020
PUMA - pooled uranium miners analysis: cohort profile.
Article in Occupational and environmental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 40 citations in OpenAlex.
- Updated cancer mortality among uranium miners on the Colorado Plateau: interactions of radon exposure with smoking and temporal factors.Occupational and environmental medicine · 2025Article
- Does radon cause diseases other than lung cancer? Findings on mortality within the German uranium miners cohort study, 1946-2018.Occupational and environmental medicine · 2025Article
- Comprehensive computational analysis via Adverse Outcome Pathways and Aggregate Exposure Pathways in exploring synergistic effects from radon and tobacco smoke on lung cancer.Frontiers in public health · 2025Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Lifetime excess absolute risk for lung cancer due to exposure to radon: results of the pooled uranium miners cohort study PUMA.Radiation and environmental biophysics · 2024Article
- Updated risk models for lung cancer due to radon exposure in the German Wismut cohort of uranium miners, 1946-2018.Radiation and environmental biophysics · 2023Article
- Radon and lung cancer in the pooled uranium miners analysis (PUMA): highly exposed early miners and all miners.Occupational and environmental medicine · 2023Article
- Progress in biological and medical research in the deep underground: an update.Frontiers in public health · 2023Review
- The epidemiology of lung cancer following radiation exposure.International journal of radiation biology · 2023Article
- Effects of spatial variation in dose delivery: what can we learn from radon-related lung cancer studies?Radiation and environmental biophysics · 2022Review
- Nonmalignant respiratory disease mortality in male Colorado Plateau uranium miners, 1960-2016.American journal of industrial medicine · 2022Article
- Lung Cancer and Radon: Pooled Analysis of Uranium Miners Hired in 1960 or Later.Environmental health perspectives · 2022Article
- Mortality in Underground Miners in a Former Uranium Ore Mine–Results of a Cohort Study Among Former Employees of Wismut AG in Saxony and Thuringia.Deutsches Arzteblatt international · 2021Article
- Cohort profile: four early uranium processing facilities in the US and Canada.International journal of radiation biology · 2021Article
- Site-specific concentration of uranium in urine of workers of the hydrometallurgical plant of Stepnogorsk mining and chemical combine.Radiation and environmental biophysics · 2020Article
- Radiation-related health hazards to uranium miners.Environmental science and pollution research international · 2020Review
- A Bayesian hierarchical approach to account for left-censored and missing radiation doses prone to classical measurement error when analyzing lung cancer mortality due to γ-ray exposure in the French cohort of uranium miners.Radiation and environmental biophysics · 2020Article
Corrections and comments
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Authors and funding
13 authors at 9 institutions in 5 countries.
Funding
Abstract
objectivesEpidemiological studies of underground miners have provided clear evidence that inhalation of radon decay products causes lung cancer. Moreover, these studies have served as a quantitative basis for estimation of radon-associated excess lung cancer risk. However, questions remain regarding the effects of exposure to the low levels of radon decay products typically encountered in contemporary occupational and environmental settings on the risk of lung cancer and other diseases, and on the modifiers of these associations. These issues are of central importance for estimation of risks associated with residential and occupational radon exposures.
methodsThe Pooled Uranium Miner Analysis (PUMA) assembles information on cohorts of uranium miners in North America and Europe. Data available include individual annual estimates of exposure to radon decay products, demographic and employment history information on each worker and information on vital status, date of death and cause of death. Some, but not all, cohorts also have individual information on cigarette smoking, external gamma radiation exposure and non-radiological occupational exposures.
resultsThe PUMA study represents the largest study of uranium miners conducted to date, encompassing 124 507 miners, 4.51 million person-years at risk and 54 462 deaths, including 7825 deaths due to lung cancer. Planned research topics include analyses of associations between radon exposure and mortality due to lung cancer, cancers other than lung, non-malignant disease, modifiers of these associations and characterisation of overall relative mortality excesses and lifetime risks.
conclusionPUMA provides opportunities to evaluate new research questions and to conduct analyses to assess potential health risks associated with uranium mining that have greater statistical power than can be achieved with any single cohort.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.